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Detailed Characterization of Mesenchymal Stem/Stromal Cells from a Large Cohort of AML Patients Demonstrates a Definitive Link to Treatment Outcomes.
Diaz de la Guardia R, Lopez-Millan B, Lavoie JR, Bueno C, Castaño J, Gómez-Casares M, Vives S, Palomo L, Juan M, Delgado J, Blanco ML, Nomdedeu J, Chaparro A, Fuster JL, Anguita E, Rosu-Myles M, Menéndez P. Diaz de la Guardia R, et al. Among authors: lavoie jr. Stem Cell Reports. 2017 Jun 6;8(6):1573-1586. doi: 10.1016/j.stemcr.2017.04.019. Epub 2017 May 18. Stem Cell Reports. 2017. PMID: 28528702 Free PMC article.
Bone marrow mesenchymal stem/stromal cells from risk-stratified acute myeloid leukemia patients are anti-inflammatory in in vivo preclinical models of hematopoietic reconstitution and severe colitis.
de la Guardia RD, Lopez-Millan B, Roca-Ho H, Bueno C, Gutiérrez-Agüera F, Fuster JL, Anguita E, Zanetti SR, Vives S, Nomdedeu J, Sackstein R, Lavoie J, Gónzalez-Rey E, Delgado M, Rosu-Myles M, Menendez P. de la Guardia RD, et al. Haematologica. 2019 Feb;104(2):e54-e58. doi: 10.3324/haematol.2018.196568. Epub 2018 Sep 20. Haematologica. 2019. PMID: 30237260 Free PMC article. No abstract available.
Hollow-fiber bioreactor production of extracellular vesicles from human bone marrow mesenchymal stromal cells yields nanovesicles that mirrors the immuno-modulatory antigenic signature of the producer cell.
Gobin J, Muradia G, Mehic J, Westwood C, Couvrette L, Stalker A, Bigelow S, Luebbert CC, Bissonnette FS, Johnston MJW, Sauvé S, Tam RY, Wang L, Rosu-Myles M, Lavoie JR. Gobin J, et al. Among authors: lavoie jr. Stem Cell Res Ther. 2021 Feb 12;12(1):127. doi: 10.1186/s13287-021-02190-3. Stem Cell Res Ther. 2021. PMID: 33579358 Free PMC article.
Uncovering the secretes of mesenchymal stem cells.
Lavoie JR, Rosu-Myles M. Lavoie JR, et al. Biochimie. 2013 Dec;95(12):2212-21. doi: 10.1016/j.biochi.2013.06.017. Epub 2013 Jun 28. Biochimie. 2013. PMID: 23810910 Review.
Therapeutic effect of the immunomodulatory drug lenalidomide, but not pomalidomide, in experimental models of rheumatoid arthritis and inflammatory bowel disease.
Lopez-Millan B, Diaz de la Guardia R, Roca-Ho H, García-Herrero CM, Lavoie JR, Rosu-Myles M, Gonzalez-Rey E, O'Valle F, Criado G, Delgado M, Menendez P. Lopez-Millan B, et al. Among authors: lavoie jr. Exp Mol Med. 2017 Feb 3;49(2):e290. doi: 10.1038/emm.2016.143. Exp Mol Med. 2017. PMID: 28154372 Free PMC article.
A comprehensive proteomics profiling identifies NRP1 as a novel identity marker of human bone marrow mesenchymal stromal cell-derived small extracellular vesicles.
Munshi A, Mehic J, Creskey M, Gobin J, Gao J, Rigg E, Muradia G, Luebbert CC, Westwood C, Stalker A, Allan DS, Johnston MJW, Cyr T, Rosu-Myles M, Lavoie JR. Munshi A, et al. Among authors: lavoie jr. Stem Cell Res Ther. 2019 Dec 18;10(1):401. doi: 10.1186/s13287-019-1516-2. Stem Cell Res Ther. 2019. PMID: 31852509 Free PMC article.
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