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A topologically diverse family of fluoride channels.
Macdonald CB, Stockbridge RB. Macdonald CB, et al. Curr Opin Struct Biol. 2017 Aug;45:142-149. doi: 10.1016/j.sbi.2017.04.003. Epub 2017 May 14. Curr Opin Struct Biol. 2017. PMID: 28514705 Free PMC article. Review.
Guanidinium export is the primal function of SMR family transporters.
Kermani AA, Macdonald CB, Gundepudi R, Stockbridge RB. Kermani AA, et al. Among authors: macdonald cb. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3060-3065. doi: 10.1073/pnas.1719187115. Epub 2018 Mar 5. Proc Natl Acad Sci U S A. 2018. PMID: 29507227 Free PMC article.
The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics.
Yee SW, Macdonald CB, Mitrovic D, Zhou X, Koleske ML, Yang J, Buitrago Silva D, Rockefeller Grimes P, Trinidad DD, More SS, Kachuri L, Witte JS, Delemotte L, Giacomini KM, Coyote-Maestas W. Yee SW, et al. Among authors: macdonald cb. Mol Cell. 2024 May 16;84(10):1932-1947.e10. doi: 10.1016/j.molcel.2024.04.008. Epub 2024 May 3. Mol Cell. 2024. PMID: 38703769
Molecular basis of proton-sensing by G protein-coupled receptors.
Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrota E, Grimes PR, Zahm A, Trinidad DD, English J, Coyote-Maestas W, Manglik A. Howard MK, et al. Among authors: macdonald cb. bioRxiv [Preprint]. 2024 Apr 18:2024.04.17.590000. doi: 10.1101/2024.04.17.590000. bioRxiv. 2024. PMID: 38659943 Free PMC article. Preprint.
Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain.
Estevam GO, Linossi EM, Macdonald CB, Espinoza CA, Michaud JM, Coyote-Maestas W, Collisson EA, Jura N, Fraser JS. Estevam GO, et al. Among authors: macdonald cb. bioRxiv [Preprint]. 2024 May 6:2023.08.03.551866. doi: 10.1101/2023.08.03.551866. bioRxiv. 2024. PMID: 37577651 Free PMC article. Preprint.
42 results