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PD-L1 expression on malignant cells is no prerequisite for checkpoint therapy.
Kleinovink JW, Marijt KA, Schoonderwoerd MJA, van Hall T, Ossendorp F, Fransen MF. Kleinovink JW, et al. Among authors: ossendorp f. Oncoimmunology. 2017 Feb 21;6(4):e1294299. doi: 10.1080/2162402X.2017.1294299. eCollection 2017. Oncoimmunology. 2017. PMID: 28507803 Free PMC article.
Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants.
van Hall T, Wolpert EZ, van Veelen P, Laban S, van der Veer M, Roseboom M, Bres S, Grufman P, de Ru A, Meiring H, de Jong A, Franken K, Teixeira A, Valentijn R, Drijfhout JW, Koning F, Camps M, Ossendorp F, Kärre K, Ljunggren HG, Melief CJ, Offringa R. van Hall T, et al. Among authors: ossendorp f. Nat Med. 2006 Apr;12(4):417-24. doi: 10.1038/nm1381. Epub 2006 Mar 19. Nat Med. 2006. PMID: 16550190
Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells.
Khan S, Bijker MS, Weterings JJ, Tanke HJ, Adema GJ, van Hall T, Drijfhout JW, Melief CJ, Overkleeft HS, van der Marel GA, Filippov DV, van der Burg SH, Ossendorp F. Khan S, et al. Among authors: ossendorp f. J Biol Chem. 2007 Jul 20;282(29):21145-59. doi: 10.1074/jbc.M701705200. Epub 2007 Apr 26. J Biol Chem. 2007. PMID: 17462991 Free article.
Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity.
van Montfoort N, Camps MG, Khan S, Filippov DV, Weterings JJ, Griffith JM, Geuze HJ, van Hall T, Verbeek JS, Melief CJ, Ossendorp F. van Montfoort N, et al. Among authors: ossendorp f. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6730-5. doi: 10.1073/pnas.0900969106. Epub 2009 Apr 3. Proc Natl Acad Sci U S A. 2009. PMID: 19346487 Free PMC article.
Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes.
Kessler JH, Khan S, Seifert U, Le Gall S, Chow KM, Paschen A, Bres-Vloemans SA, de Ru A, van Montfoort N, Franken KL, Benckhuijsen WE, Brooks JM, van Hall T, Ray K, Mulder A, Doxiadis II, van Swieten PF, Overkleeft HS, Prat A, Tomkinson B, Neefjes J, Kloetzel PM, Rodgers DW, Hersh LB, Drijfhout JW, van Veelen PA, Ossendorp F, Melief CJ. Kessler JH, et al. Among authors: ossendorp f. Nat Immunol. 2011 Jan;12(1):45-53. doi: 10.1038/ni.1974. Epub 2010 Dec 12. Nat Immunol. 2011. PMID: 21151101
218 results