The essential role of phospho-T38 CPI-17 in the maintenance of physiological blood pressure using genetically modified mice.
Yang Q, Fujii W, Kaji N, Kakuta S, Kada K, Kuwahara M, Tsubone H, Ozaki H, Hori M.
Yang Q, et al. Among authors: kaji n.
FASEB J. 2018 Apr;32(4):2095-2109. doi: 10.1096/fj.201700794R. Epub 2018 Jan 5.
FASEB J. 2018.
PMID: 29229685
In summary, we generated KO and constitutively phospho-resistant mouse models of CPI-17 for the first time. p-CPI-17 at T38, possibly by PKC, could be important to maintain vascular contractility and blood pressure in vivo. -Yang, Q., Fujii, W., Kaji, N., Kakuta, S. …
In summary, we generated KO and constitutively phospho-resistant mouse models of CPI-17 for the first time. p-CPI-17 at T38, possibly by PKC …