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The Sin3a repressor complex is a master regulator of STAT transcriptional activity.
Icardi L, Mori R, Gesellchen V, Eyckerman S, De Cauwer L, Verhelst J, Vercauteren K, Saelens X, Meuleman P, Leroux-Roels G, De Bosscher K, Boutros M, Tavernier J. Icardi L, et al. Among authors: eyckerman s. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12058-63. doi: 10.1073/pnas.1206458109. Epub 2012 Jul 10. Proc Natl Acad Sci U S A. 2012. PMID: 22783022 Free PMC article.
Proteome-scale Binary Interactomics in Human Cells.
Lievens S, Van der Heyden J, Masschaele D, De Ceuninck L, Petta I, Gupta S, De Puysseleyr V, Vauthier V, Lemmens I, De Clercq DJ, Defever D, Vanderroost N, De Smet AS, Eyckerman S, Van Calenbergh S, Martens L, De Bosscher K, Libert C, Hill DE, Vidal M, Tavernier J. Lievens S, et al. Among authors: eyckerman s. Mol Cell Proteomics. 2016 Dec;15(12):3624-3639. doi: 10.1074/mcp.M116.061994. Epub 2016 Nov 1. Mol Cell Proteomics. 2016. PMID: 27803151 Free PMC article.
Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets.
Van Moortel L, Thommis J, Maertens B, Staes A, Clarisse D, De Sutter D, Libert C, Meijer OC, Eyckerman S, Gevaert K, De Bosscher K. Van Moortel L, et al. Among authors: eyckerman s. Biomed Pharmacother. 2022 Aug;152:113218. doi: 10.1016/j.biopha.2022.113218. Epub 2022 Jun 13. Biomed Pharmacother. 2022. PMID: 35709653 Free article.
Selective Modulation of the Human Glucocorticoid Receptor Compromises GR Chromatin Occupancy and Recruitment of p300/CBP and the Mediator Complex.
Van Moortel L, Verhee A, Thommis J, Houtman R, Melchers D, Delhaye L, Van Leene C, Hellemans M, Gevaert K, Eyckerman S, De Bosscher K. Van Moortel L, et al. Among authors: eyckerman s. Mol Cell Proteomics. 2024 Mar;23(3):100741. doi: 10.1016/j.mcpro.2024.100741. Epub 2024 Feb 20. Mol Cell Proteomics. 2024. PMID: 38387774 Free PMC article.
Analyzing trapped protein complexes by Virotrap and SFINX.
Titeca K, Van Quickelberghe E, Samyn N, De Sutter D, Verhee A, Gevaert K, Tavernier J, Eyckerman S. Titeca K, et al. Among authors: eyckerman s. Nat Protoc. 2017 May;12(5):881-898. doi: 10.1038/nprot.2017.014. Epub 2017 Mar 30. Nat Protoc. 2017. PMID: 28358392
72 results