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Alzheimer's disease Advax(CpG)- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Aβ pathological molecules.
Davtyan H, Zagorski K, Rajapaksha H, Hovakimyan A, Davtyan A, Petrushina I, Kazarian K, Cribbs DH, Petrovsky N, Agadjanyan MG, Ghochikyan A. Davtyan H, et al. Among authors: kazarian k. Sci Rep. 2016 Jul 1;6:28912. doi: 10.1038/srep28912. Sci Rep. 2016. PMID: 27363809 Free PMC article.
MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice.
Davtyan H, Chen WW, Zagorski K, Davis J, Petrushina I, Kazarian K, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. Davtyan H, et al. Among authors: kazarian k. Vaccine. 2017 Apr 11;35(16):2015-2024. doi: 10.1016/j.vaccine.2017.03.020. Epub 2017 Mar 18. Vaccine. 2017. PMID: 28320590 Free PMC article.
MultiTEP platform-based DNA vaccines for alpha-synucleinopathies: preclinical evaluation of immunogenicity and therapeutic potency.
Davtyan H, Zagorski K, Petrushina I, Kazarian K, Goldberg NRS, Petrosyan J, Blurton-Jones M, Masliah E, Cribbs DH, Agadjanyan MG, Ghochikyan A. Davtyan H, et al. Among authors: kazarian k. Neurobiol Aging. 2017 Nov;59:156-170. doi: 10.1016/j.neurobiolaging.2017.08.006. Epub 2017 Aug 10. Neurobiol Aging. 2017. PMID: 28870518 Free PMC article.
Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials.
Petrushina I, Hovakimyan A, Harahap-Carrillo IS, Davtyan H, Antonyan T, Chailyan G, Kazarian K, Antonenko M, Jullienne A, Hamer MM, Obenaus A, King O, Zagorski K, Blurton-Jones M, Cribbs DH, Lander H, Ghochikyan A, Agadjanyan MG. Petrushina I, et al. Among authors: kazarian k. Neurobiol Dis. 2020 Jun;139:104823. doi: 10.1016/j.nbd.2020.104823. Epub 2020 Feb 28. Neurobiol Dis. 2020. PMID: 32119976 Free PMC article. Review.
Performance of a cryo-cooled crystal monochromator illuminated by hard X-rays with MHz repetition rate at the European X-ray Free-Electron Laser.
Petrov I, Boesenberg U, Bushuev VA, Hallmann J, Kazarian K, Lu W, Möller J, Reiser M, Rodriguez-Fernandez A, Samoylova L, Scholz M, Sinn H, Zozulya A, Madsen A. Petrov I, et al. Among authors: kazarian k. Opt Express. 2022 Feb 14;30(4):4978-4987. doi: 10.1364/OE.451110. Opt Express. 2022. PMID: 35209469 Free article.
Materials Imaging and Dynamics (MID) instrument at the European X-ray Free-Electron Laser Facility.
Madsen A, Hallmann J, Ansaldi G, Roth T, Lu W, Kim C, Boesenberg U, Zozulya A, Möller J, Shayduk R, Scholz M, Bartmann A, Schmidt A, Lobato I, Sukharnikov K, Reiser M, Kazarian K, Petrov I. Madsen A, et al. Among authors: kazarian k. J Synchrotron Radiat. 2021 Mar 1;28(Pt 2):637-649. doi: 10.1107/S1600577521001302. Epub 2021 Feb 15. J Synchrotron Radiat. 2021. PMID: 33650576 Free PMC article.
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