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Antiangiogenic platinum through glycan targeting.
Peterson EJ, Daniel AG, Katner SJ, Bohlmann L, Chang CW, Bezos A, Parish CR, von Itzstein M, Berners-Price SJ, Farrell NP. Peterson EJ, et al. Among authors: von itzstein m. Chem Sci. 2017 Jan 1;8(1):241-252. doi: 10.1039/c6sc02515c. Epub 2016 Aug 12. Chem Sci. 2017. PMID: 28451171 Free PMC article.
Functional and structural characterization of a heparanase.
Bohlmann L, Tredwell GD, Yu X, Chang CW, Haselhorst T, Winger M, Dyason JC, Thomson RJ, Tiralongo J, Beacham IR, Blanchard H, von Itzstein M. Bohlmann L, et al. Among authors: von itzstein m. Nat Chem Biol. 2015 Dec;11(12):955-7. doi: 10.1038/nchembio.1956. Epub 2015 Nov 2. Nat Chem Biol. 2015. PMID: 26565989
Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance.
Bohlmann L, De Oliveira DMP, El-Deeb IM, Brazel EB, Harbison-Price N, Ong CY, Rivera-Hernandez T, Ferguson SA, Cork AJ, Phan MD, Soderholm AT, Davies MR, Nimmo GR, Dougan G, Schembri MA, Cook GM, McEwan AG, von Itzstein M, McDevitt CA, Walker MJ. Bohlmann L, et al. Among authors: von itzstein m. mBio. 2018 Dec 11;9(6):e02391-18. doi: 10.1128/mBio.02391-18. mBio. 2018. PMID: 30538186 Free PMC article.
Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2.
Harbison-Price N, Ferguson SA, Heikal A, Taiaroa G, Hards K, Nakatani Y, Rennison D, Brimble MA, El-Deeb IM, Bohlmann L, McDevitt CA, von Itzstein M, Walker MJ, Cook GM. Harbison-Price N, et al. Among authors: von itzstein m. mSphere. 2020 Mar 18;5(2):e00157-20. doi: 10.1128/mSphere.00157-20. mSphere. 2020. PMID: 32188750 Free PMC article.
Conformational Modulation of Iduronic Acid-Containing Sulfated Glycosaminoglycans by a Polynuclear Platinum Compound and Implications for Development of Antimetastatic Platinum Drugs.
Gorle AK, Haselhorst T, Katner SJ, Everest-Dass AV, Hampton JD, Peterson EJ, Koblinski JE, Katsuta E, Takabe K, von Itzstein M, Berners-Price SJ, Farrell NP. Gorle AK, et al. Among authors: von itzstein m. Angew Chem Int Ed Engl. 2021 Feb 8;60(6):3283-3289. doi: 10.1002/anie.202013749. Epub 2020 Dec 23. Angew Chem Int Ed Engl. 2021. PMID: 33174390 Free PMC article.
Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis.
De Oliveira DMP, Bohlmann L, Conroy T, Jen FE, Everest-Dass A, Hansford KA, Bolisetti R, El-Deeb IM, Forde BM, Phan MD, Lacey JA, Tan A, Rivera-Hernandez T, Brouwer S, Keller N, Kidd TJ, Cork AJ, Bauer MJ, Cook GM, Davies MR, Beatson SA, Paterson DL, McEwan AG, Li J, Schembri MA, Blaskovich MAT, Jennings MP, McDevitt CA, von Itzstein M, Walker MJ. De Oliveira DMP, et al. Among authors: von itzstein m. Sci Transl Med. 2020 Nov 18;12(570):eabb3791. doi: 10.1126/scitranslmed.abb3791. Sci Transl Med. 2020. PMID: 33208501
242 results