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Intravenous administration of Reolysin, a live replication competent RNA virus is safe in patients with advanced solid tumors.
Gollamudi R, Ghalib MH, Desai KK, Chaudhary I, Wong B, Einstein M, Coffey M, Gill GM, Mettinger K, Mariadason JM, Mani S, Goel S. Gollamudi R, et al. Among authors: coffey m. Invest New Drugs. 2010 Oct;28(5):641-9. doi: 10.1007/s10637-009-9279-8. Epub 2009 Jul 2. Invest New Drugs. 2010. PMID: 19572105 Free PMC article. Clinical Trial.
Oncolytic reovirus in combination with chemotherapy in metastatic or recurrent non-small cell lung cancer patients with KRAS-activated tumors.
Villalona-Calero MA, Lam E, Otterson GA, Zhao W, Timmons M, Subramaniam D, Hade EM, Gill GM, Coffey M, Selvaggi G, Bertino E, Chao B, Knopp MV. Villalona-Calero MA, et al. Among authors: coffey m. Cancer. 2016 Mar 15;122(6):875-83. doi: 10.1002/cncr.29856. Epub 2015 Dec 28. Cancer. 2016. PMID: 26709987 Free PMC article.
Reovirus oncolysis of human breast cancer.
Norman KL, Coffey MC, Hirasawa K, Demetrick DJ, Nishikawa SG, DiFrancesco LM, Strong JE, Lee PW. Norman KL, et al. Among authors: coffey mc. Hum Gene Ther. 2002 Mar 20;13(5):641-52. doi: 10.1089/10430340252837233. Hum Gene Ther. 2002. PMID: 11916487
Oncolytic viral therapy for prostate cancer: efficacy of reovirus as a biological therapeutic.
Thirukkumaran CM, Nodwell MJ, Hirasawa K, Shi ZQ, Diaz R, Luider J, Johnston RN, Forsyth PA, Magliocco AM, Lee P, Nishikawa S, Donnelly B, Coffey M, Trpkov K, Fonseca K, Spurrell J, Morris DG. Thirukkumaran CM, et al. Among authors: coffey m. Cancer Res. 2010 Mar 15;70(6):2435-44. doi: 10.1158/0008-5472.CAN-09-2408. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215509
739 results