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Heptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapy.
Jézégou A, Llinares E, Anne C, Kieffer-Jaquinod S, O'Regan S, Aupetit J, Chabli A, Sagné C, Debacker C, Chadefaux-Vekemans B, Journet A, André B, Gasnier B. Jézégou A, et al. Among authors: gasnier b. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):E3434-43. doi: 10.1073/pnas.1211198109. Epub 2012 Nov 20. Proc Natl Acad Sci U S A. 2012. PMID: 23169667 Free PMC article.
An extended proteome map of the lysosomal membrane reveals novel potential transporters.
Chapel A, Kieffer-Jaquinod S, Sagné C, Verdon Q, Ivaldi C, Mellal M, Thirion J, Jadot M, Bruley C, Garin J, Gasnier B, Journet A. Chapel A, et al. Among authors: gasnier b. Mol Cell Proteomics. 2013 Jun;12(6):1572-88. doi: 10.1074/mcp.M112.021980. Epub 2013 Feb 24. Mol Cell Proteomics. 2013. PMID: 23436907 Free PMC article.
Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B12-trafficking proteins ABCD4 and LMBD1.
Fettelschoss V, Burda P, Sagné C, Coelho D, De Laet C, Lutz S, Suormala T, Fowler B, Pietrancosta N, Gasnier B, Bornhauser B, Froese DS, Baumgartner MR. Fettelschoss V, et al. Among authors: gasnier b. J Biol Chem. 2017 Jul 14;292(28):11980-11991. doi: 10.1074/jbc.M117.784819. Epub 2017 Jun 1. J Biol Chem. 2017. PMID: 28572511 Free PMC article.
Successful prediction of substrate-binding pocket in SLC17 transporter sialin.
Pietrancosta N, Anne C, Prescher H, Ruivo R, Sagné C, Debacker C, Bertrand HO, Brossmer R, Acher F, Gasnier B. Pietrancosta N, et al. Among authors: gasnier b. J Biol Chem. 2012 Mar 30;287(14):11489-97. doi: 10.1074/jbc.M111.313056. Epub 2012 Feb 13. J Biol Chem. 2012. PMID: 22334707 Free PMC article.
66 results