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Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor.
Paparin JL, Amador A, Badaroux E, Bot S, Caillet C, Convard T, Da Costa D, Dukhan D, Griffe L, Griffon JF, LaColla M, Leroy F, Liuzzi M, Giulia Loi A, McCarville J, Mascia V, Milhau J, Onidi L, Pierra C, Rahali R, Rosinosky E, Sais E, Seifer M, Surleraux D, Standring D, Dousson CB. Paparin JL, et al. Among authors: griffe l. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2634-2640. doi: 10.1016/j.bmcl.2017.01.017. Epub 2017 Jan 13. Bioorg Med Chem Lett. 2017. PMID: 28416131
Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.
Pierra Rouvière C, Amador A, Badaroux E, Convard T, Da Costa D, Dukhan D, Griffe L, Griffon JF, LaColla M, Leroy F, Liuzzi M, Loi AG, McCarville J, Mascia V, Milhau J, Onidi L, Paparin JL, Rahali R, Sais E, Seifer M, Surleraux D, Standring D, Dousson C. Pierra Rouvière C, et al. Among authors: griffe l. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4536-4541. doi: 10.1016/j.bmcl.2016.01.042. Epub 2016 Jan 22. Bioorg Med Chem Lett. 2016. PMID: 27520942
Characterisation of barley landraces from Syria and Jordan for resistance to rhynchosporium and identification of diagnostic markers for Rrs1Rh4.
Looseley ME, Griffe LL, Büttner B, Wright KM, Bayer MM, Coulter M, Thauvin JN, Middlefell-Williams J, Maluk M, Okpo A, Kettles N, Werner P, Byrne E, Avrova A. Looseley ME, et al. Among authors: griffe ll. Theor Appl Genet. 2020 Apr;133(4):1243-1264. doi: 10.1007/s00122-020-03545-9. Epub 2020 Jan 22. Theor Appl Genet. 2020. PMID: 31965232
Resistance to Rhynchosporium commune in a collection of European spring barley germplasm.
Looseley ME, Griffe LL, Büttner B, Wright KM, Middlefell-Williams J, Bull H, Shaw PD, Macaulay M, Booth A, Schweizer G, Russell JR, Waugh R, Thomas WTB, Avrova A. Looseley ME, et al. Among authors: griffe ll. Theor Appl Genet. 2018 Dec;131(12):2513-2528. doi: 10.1007/s00122-018-3168-5. Epub 2018 Aug 27. Theor Appl Genet. 2018. PMID: 30151748
15 results