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A new CysLT1 and CysLT2 receptors-mediated anaphylaxis guinea pig model.
Sekioka T, Kadode M, Osakada N, Fujita M, Matsumura N, Yamaura Y, Nakade S, Nabe T, Kawabata K. Sekioka T, et al. Among authors: yamaura y. Prostaglandins Leukot Essent Fatty Acids. 2017 Apr;119:18-24. doi: 10.1016/j.plefa.2017.03.002. Epub 2017 Mar 8. Prostaglandins Leukot Essent Fatty Acids. 2017. PMID: 28410666
Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma.
Itadani S, Yashiro K, Aratani Y, Sekiguchi T, Kinoshita A, Moriguchi H, Ohta N, Takahashi S, Ishida A, Tajima Y, Hisaichi K, Ima M, Ueda J, Egashira H, Sekioka T, Kadode M, Yonetomi Y, Nakao T, Inoue A, Nomura H, Kitamine T, Fujita M, Nabe T, Yamaura Y, Matsumura N, Imagawa A, Nakayama Y, Takeuchi J, Ohmoto K. Itadani S, et al. Among authors: yamaura y. J Med Chem. 2015 Aug 13;58(15):6093-113. doi: 10.1021/acs.jmedchem.5b00741. Epub 2015 Jul 22. J Med Chem. 2015. PMID: 26200813
Age-related changes of hepatic clearances of cytochrome P450 probes, midazolam and R-/S-warfarin in combination with caffeine, omeprazole and metoprolol in cynomolgus monkeys using in vitro-in vivo correlation.
Koyanagi T, Nakanishi Y, Murayama N, Yamaura Y, Ikeda K, Yano K, Uehara S, Utoh M, Kim S, Uno Y, Yamazaki H. Koyanagi T, et al. Among authors: yamaura y. Xenobiotica. 2015 Apr;45(4):312-21. doi: 10.3109/00498254.2014.979271. Epub 2014 Nov 3. Xenobiotica. 2015. PMID: 25364857
3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 3: Synthesis, metabolic stability, and biological evaluation of optically active analogs.
Asada M, Obitsu T, Kinoshita A, Nagase T, Yoshida T, Yamaura Y, Takizawa H, Yoshikawa K, Sato K, Narita M, Nakai H, Toda M, Tobe Y. Asada M, et al. Among authors: yamaura y. Bioorg Med Chem. 2010 May 1;18(9):3212-23. doi: 10.1016/j.bmc.2010.03.028. Epub 2010 Mar 17. Bioorg Med Chem. 2010. PMID: 20385498
126 results