Fujita M - Search Results

1

A new CysLT₁ and CysLT₂ receptors-mediated anaphylaxis guinea pig model.

Sekioka T, Kadode M, Osakada N, Fujita M, Matsumura N, Yamaura Y, Nakade S, Nabe T, Kawabata K. Sekioka T, et al. Among authors: fujita m. Prostaglandins Leukot Essent Fatty Acids. 2017 Apr;119:18-24. doi: 10.1016/j.plefa.2017.03.002. Epub 2017 Mar 8. Prostaglandins Leukot Essent Fatty Acids. 2017. PMID: 28410666

2

Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma.

Itadani S, Yashiro K, Aratani Y, Sekiguchi T, Kinoshita A, Moriguchi H, Ohta N, Takahashi S, Ishida A, Tajima Y, Hisaichi K, Ima M, Ueda J, Egashira H, Sekioka T, Kadode M, Yonetomi Y, Nakao T, Inoue A, Nomura H, Kitamine T, Fujita M, Nabe T, Yamaura Y, Matsumura N, Imagawa A, Nakayama Y, Takeuchi J, Ohmoto K. Itadani S, et al. Among authors: fujita m. J Med Chem. 2015 Aug 13;58(15):6093-113. doi: 10.1021/acs.jmedchem.5b00741. Epub 2015 Jul 22. J Med Chem. 2015. PMID: 26200813

3

Effects of ONO-6950, a novel dual cysteinyl leukotriene 1 and 2 receptors antagonist, in a guinea pig model of asthma.

Yonetomi Y, Sekioka T, Kadode M, Kitamine T, Kamiya A, inoue A, Nakao T, Nomura H, Murata M, Nakao S, Nambu F, Fujita M, Nakade S, Kawabata K. Yonetomi Y, et al. Among authors: fujita m. Eur J Pharmacol. 2015 Oct 15;765:242-8. doi: 10.1016/j.ejphar.2015.08.041. Epub 2015 Aug 28. Eur J Pharmacol. 2015. PMID: 26318198

4

CysLT₂ receptor activation is involved in LTC₄-induced lung air-trapping in guinea pigs.

Sekioka T, Kadode M, Yonetomi Y, Kamiya A, Fujita M, Nabe T, Kawabata K. Sekioka T, et al. Among authors: fujita m. Eur J Pharmacol. 2017 Jan 5;794:147-153. doi: 10.1016/j.ejphar.2016.11.036. Epub 2016 Nov 22. Eur J Pharmacol. 2017. PMID: 27887950

5

Leukotriene C4 induces bronchoconstriction and airway vascular hyperpermeability via the cysteinyl leukotriene receptor 2 in S-hexyl glutathione-treated guinea pigs.

Yonetomi Y, Sekioka T, Kadode M, Kitamine T, Kamiya A, Matsumura N, Fujita M, Kawabata K. Yonetomi Y, et al. Among authors: fujita m. Eur J Pharmacol. 2015 May 5;754:98-104. doi: 10.1016/j.ejphar.2015.02.014. Epub 2015 Feb 20. Eur J Pharmacol. 2015. PMID: 25704617

6

Effects of a specific cysteinyl leukotriene antagonist, pranlukast, on antigen-induced cysteinyl leukotriene-mediated rhinitis in guinea pigs.

Fujita M, Yonetomi Y, Takeda H, Nakagawa N, Kawabata K, Ohno H. Fujita M, et al. Jpn J Pharmacol. 1997 Dec;75(4):347-53. doi: 10.1254/jjp.75.347. Jpn J Pharmacol. 1997. PMID: 9469640 Free article.

7

Cysteinyl leukotrienes induce nasal symptoms of allergic rhinitis via a receptor-mediated mechanism in guinea pigs.

Fujita M, Nakagawa N, Yonetomi Y, Takeda H, Kawabata K, Ohno H. Fujita M, et al. Jpn J Pharmacol. 1997 Dec;75(4):355-62. doi: 10.1254/jjp.75.355. Jpn J Pharmacol. 1997. PMID: 9469641 Free article.

8

Involvement of cysteinyl leukotrienes in biphasic increase of nasal airway resistance of antigen-induced rhinitis in guinea pigs.

Fujita M, Yonetomi Y, Shimouchi K, Takeda H, Aze Y, Kawabata K, Ohno H. Fujita M, et al. Eur J Pharmacol. 1999 Mar 26;369(3):349-56. doi: 10.1016/s0014-2999(99)00037-0. Eur J Pharmacol. 1999. PMID: 10225374

9

Discovery of a potent, orally available dual CysLT₁ and CysLT₂ antagonist with dicarboxylic acid.

Itadani S, Takahashi S, Ima M, Sekiguchi T, Aratani Y, Egashira H, Matsumura N, Inoue A, Yonetomi Y, Fujita M, Nakayama Y, Takeuchi J. Itadani S, et al. Among authors: fujita m. Bioorg Med Chem. 2015 May 1;23(9):2079-97. doi: 10.1016/j.bmc.2015.03.011. Epub 2015 Mar 7. Bioorg Med Chem. 2015. PMID: 25800431

10

Discovery of Highly Potent Dual CysLT1 and CysLT2 Antagonist.

Itadani S, Takahashi S, Ima M, Sekiguchi T, Fujita M, Nakayama Y, Takeuchi J. Itadani S, et al. Among authors: fujita m. ACS Med Chem Lett. 2014 Oct 6;5(11):1230-4. doi: 10.1021/ml500298y. eCollection 2014 Nov 13. ACS Med Chem Lett. 2014. PMID: 25408836 Free PMC article.

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