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Page 1
Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model.
Sociali G, Magnone M, Ravera S, Damonte P, Vigliarolo T, Von Holtey M, Vellone VG, Millo E, Caffa I, Cea M, Parenti MD, Del Rio A, Murone M, Mostoslavsky R, Grozio A, Nencioni A, Bruzzone S. Sociali G, et al. Among authors: mostoslavsky r. FASEB J. 2017 Jul;31(7):3138-3149. doi: 10.1096/fj.201601294R. Epub 2017 Apr 6. FASEB J. 2017. PMID: 28386046 Free PMC article.
., Caffa, I., Cea, M., Parenti, M. D., Del Rio, A., Murone, M., Mostoslavsky, R., Grozio, A., Nencioni, A., Bruzzone S. Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model....
., Caffa, I., Cea, M., Parenti, M. D., Del Rio, A., Murone, M., Mostoslavsky, R., Grozio, A., Nencioni, A., Bruzzone S. Pharma …
Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.
Bruzzone S, Fruscione F, Morando S, Ferrando T, Poggi A, Garuti A, D'Urso A, Selmo M, Benvenuto F, Cea M, Zoppoli G, Moran E, Soncini D, Ballestrero A, Sordat B, Patrone F, Mostoslavsky R, Uccelli A, Nencioni A. Bruzzone S, et al. Among authors: mostoslavsky r. PLoS One. 2009 Nov 19;4(11):e7897. doi: 10.1371/journal.pone.0007897. PLoS One. 2009. PMID: 19936064 Free PMC article.
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha.
Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R. Zhong L, et al. Among authors: mostoslavsky r. Cell. 2010 Jan 22;140(2):280-93. doi: 10.1016/j.cell.2009.12.041. Cell. 2010. PMID: 20141841 Free PMC article.
Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction.
Montecucco F, Bauer I, Braunersreuther V, Bruzzone S, Akhmedov A, Lüscher TF, Speer T, Poggi A, Mannino E, Pelli G, Galan K, Bertolotto M, Lenglet S, Garuti A, Montessuit C, Lerch R, Pellieux C, Vuilleumier N, Dallegri F, Mage J, Sebastian C, Mostoslavsky R, Gayet-Ageron A, Patrone F, Mach F, Nencioni A. Montecucco F, et al. Among authors: mostoslavsky r. Antioxid Redox Signal. 2013 Feb 20;18(6):630-41. doi: 10.1089/ars.2011.4487. Epub 2012 May 14. Antioxid Redox Signal. 2013. PMID: 22452634 Free PMC article.
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses.
Bauer I, Grozio A, Lasigliè D, Basile G, Sturla L, Magnone M, Sociali G, Soncini D, Caffa I, Poggi A, Zoppoli G, Cea M, Feldmann G, Mostoslavsky R, Ballestrero A, Patrone F, Bruzzone S, Nencioni A. Bauer I, et al. Among authors: mostoslavsky r. J Biol Chem. 2012 Nov 30;287(49):40924-37. doi: 10.1074/jbc.M112.405837. Epub 2012 Oct 18. J Biol Chem. 2012. PMID: 23086953 Free PMC article.
Sirt6 regulates dendritic cell differentiation, maturation, and function.
Lasigliè D, Boero S, Bauer I, Morando S, Damonte P, Cea M, Monacelli F, Odetti P, Ballestrero A, Uccelli A, Mostoslavsky R, Poggi A, Nencioni A. Lasigliè D, et al. Among authors: mostoslavsky r. Aging (Albany NY). 2016 Jan;8(1):34-49. doi: 10.18632/aging.100870. Aging (Albany NY). 2016. PMID: 26761436 Free PMC article.
From sirtuin biology to human diseases: an update.
Sebastián C, Satterstrom FK, Haigis MC, Mostoslavsky R. Sebastián C, et al. Among authors: mostoslavsky r. J Biol Chem. 2012 Dec 14;287(51):42444-52. doi: 10.1074/jbc.R112.402768. Epub 2012 Oct 18. J Biol Chem. 2012. PMID: 23086954 Free PMC article. Review.
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.
Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, MacDonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R. Sebastián C, et al. Among authors: mostoslavsky r. Cell. 2012 Dec 7;151(6):1185-99. doi: 10.1016/j.cell.2012.10.047. Cell. 2012. PMID: 23217706 Free PMC article.
117 results