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CRISPR-Cas: Adapting to change.
Jackson SA, McKenzie RE, Fagerlund RD, Kieper SN, Fineran PC, Brouns SJ. Jackson SA, et al. Among authors: brouns sj. Science. 2017 Apr 7;356(6333):eaal5056. doi: 10.1126/science.aal5056. Epub 2017 Apr 6. Science. 2017. PMID: 28385959 Review.
Small CRISPR RNAs guide antiviral defense in prokaryotes.
Brouns SJ, Jore MM, Lundgren M, Westra ER, Slijkhuis RJ, Snijders AP, Dickman MJ, Makarova KS, Koonin EV, van der Oost J. Brouns SJ, et al. Science. 2008 Aug 15;321(5891):960-4. doi: 10.1126/science.1159689. Science. 2008. PMID: 18703739 Free PMC article.
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3.
Westra ER, van Erp PB, Künne T, Wong SP, Staals RH, Seegers CL, Bollen S, Jore MM, Semenova E, Severinov K, de Vos WM, Dame RT, de Vries R, Brouns SJ, van der Oost J. Westra ER, et al. Among authors: brouns sj. Mol Cell. 2012 Jun 8;46(5):595-605. doi: 10.1016/j.molcel.2012.03.018. Epub 2012 Apr 19. Mol Cell. 2012. PMID: 22521689 Free PMC article.
Degenerate target sites mediate rapid primed CRISPR adaptation.
Fineran PC, Gerritzen MJ, Suárez-Diez M, Künne T, Boekhorst J, van Hijum SA, Staals RH, Brouns SJ. Fineran PC, et al. Among authors: brouns sj. Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):E1629-38. doi: 10.1073/pnas.1400071111. Epub 2014 Apr 7. Proc Natl Acad Sci U S A. 2014. PMID: 24711427 Free PMC article.
106 results