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Page 1
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.
Vennin C, Chin VT, Warren SC, Lucas MC, Herrmann D, Magenau A, Melenec P, Walters SN, Del Monte-Nieto G, Conway JR, Nobis M, Allam AH, McCloy RA, Currey N, Pinese M, Boulghourjian A, Zaratzian A, Adam AA, Heu C, Nagrial AM, Chou A, Steinmann A, Drury A, Froio D, Giry-Laterriere M, Harris NL, Phan T, Jain R, Weninger W, McGhee EJ, Whan R, Johns AL, Samra JS, Chantrill L, Gill AJ, Kohonen-Corish M, Harvey RP, Biankin AV; Australian Pancreatic Cancer Genome Initiative (APGI); Evans TR, Anderson KI, Grey ST, Ormandy CJ, Gallego-Ortega D, Wang Y, Samuel MS, Sansom OJ, Burgess A, Cox TR, Morton JP, Pajic M, Timpson P. Vennin C, et al. Among authors: phan t. Sci Transl Med. 2017 Apr 5;9(384):eaai8504. doi: 10.1126/scitranslmed.aai8504. Sci Transl Med. 2017. PMID: 28381539 Free PMC article.
Removing physiological motion from intravital and clinical functional imaging data.
Warren SC, Nobis M, Magenau A, Mohammed YH, Herrmann D, Moran I, Vennin C, Conway JR, Mélénec P, Cox TR, Wang Y, Morton JP, Welch HC, Strathdee D, Anderson KI, Phan TG, Roberts MS, Timpson P. Warren SC, et al. Elife. 2018 Jul 9;7:e35800. doi: 10.7554/eLife.35800. Elife. 2018. PMID: 29985127 Free PMC article.
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption.
McDonald MM, Khoo WH, Ng PY, Xiao Y, Zamerli J, Thatcher P, Kyaw W, Pathmanandavel K, Grootveld AK, Moran I, Butt D, Nguyen A, Corr A, Warren S, Biro M, Butterfield NC, Guilfoyle SE, Komla-Ebri D, Dack MRG, Dewhurst HF, Logan JG, Li Y, Mohanty ST, Byrne N, Terry RL, Simic MK, Chai R, Quinn JMW, Youlten SE, Pettitt JA, Abi-Hanna D, Jain R, Weninger W, Lundberg M, Sun S, Ebetino FH, Timpson P, Lee WM, Baldock PA, Rogers MJ, Brink R, Williams GR, Bassett JHD, Kemp JP, Pavlos NJ, Croucher PI, Phan TG. McDonald MM, et al. Among authors: phan tg. Cell. 2021 Mar 4;184(5):1330-1347.e13. doi: 10.1016/j.cell.2021.02.002. Epub 2021 Feb 25. Cell. 2021. PMID: 33636130 Free PMC article.
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse.
Conway JRW, Warren SC, Lee YK, McCulloch AT, Magenau A, Lee V, Metcalf XL, Stoehr J, Haigh K, Abdulkhalek L, Guaman CS, Reed DA, Murphy KJ, Pereira BA, Mélénec P, Chambers C, Latham SL, Lenthall H, Deenick EK, Ma Y, Phan T, Lim E, Joshua AM, Walters S, Grey ST, Shi YC, Zhang L, Herzog H, Croucher DR, Philp A, Scheele CLGJ, Herrmann D, Sansom OJ, Morton JP, Papa A, Haigh JJ, Nobis M, Timpson P. Conway JRW, et al. Among authors: phan t. Sci Adv. 2023 Apr 28;9(17):eadf9063. doi: 10.1126/sciadv.adf9063. Epub 2023 Apr 26. Sci Adv. 2023. PMID: 37126544 Free PMC article.
Invasion-Block and S-MARVEL: A high-content screening and image analysis platform identifies ATM kinase as a modulator of melanoma invasion and metastasis.
Guo D, Jurek R, Beaumont KA, Sharp DS, Tan SY, Mariana A, Failes TW, Grootveld AK, Bhattacharyya ND, Phan TG, Arndt GM, Jain R, Weninger W, Tikoo S. Guo D, et al. Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2303978120. doi: 10.1073/pnas.2303978120. Epub 2023 Nov 14. Proc Natl Acad Sci U S A. 2023. PMID: 37963252 Free PMC article.
The dormant cancer cell life cycle.
Phan TG, Croucher PI. Phan TG, et al. Nat Rev Cancer. 2020 Jul;20(7):398-411. doi: 10.1038/s41568-020-0263-0. Epub 2020 Jun 2. Nat Rev Cancer. 2020. PMID: 32488200 Review.
Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer.
Junankar S, Shay G, Jurczyluk J, Ali N, Down J, Pocock N, Parker A, Nguyen A, Sun S, Kashemirov B, McKenna CE, Croucher PI, Swarbrick A, Weilbaecher K, Phan TG, Rogers MJ. Junankar S, et al. Cancer Discov. 2015 Jan;5(1):35-42. doi: 10.1158/2159-8290.CD-14-0621. Epub 2014 Oct 13. Cancer Discov. 2015. PMID: 25312016 Free PMC article.
Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche.
Lawson MA, McDonald MM, Kovacic N, Hua Khoo W, Terry RL, Down J, Kaplan W, Paton-Hough J, Fellows C, Pettitt JA, Neil Dear T, Van Valckenborgh E, Baldock PA, Rogers MJ, Eaton CL, Vanderkerken K, Pettit AR, Quinn JM, Zannettino AC, Phan TG, Croucher PI. Lawson MA, et al. Among authors: phan tg. Nat Commun. 2015 Dec 3;6:8983. doi: 10.1038/ncomms9983. Nat Commun. 2015. PMID: 26632274 Free PMC article.
2,163 results