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Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione.
Peracchi A, Veiga-da-Cunha M, Kuhara T, Ellens KW, Paczia N, Stroobant V, Seliga AK, Marlaire S, Jaisson S, Bommer GT, Sun J, Huebner K, Linster CL, Cooper AJL, Van Schaftingen E. Peracchi A, et al. Among authors: sun j. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3233-E3242. doi: 10.1073/pnas.1613736114. Epub 2017 Apr 3. Proc Natl Acad Sci U S A. 2017. PMID: 28373563 Free PMC article.
Nit1 and Fhit tumor suppressor activities are additive.
Sun J, Okumura H, Yearsley M, Frankel W, Fong LY, Druck T, Huebner K. Sun J, et al. J Cell Biochem. 2009 Aug 15;107(6):1097-106. doi: 10.1002/jcb.22207. J Cell Biochem. 2009. PMID: 19479888 Free PMC article.
Hits, Fhits and Nits: beyond enzymatic function.
Huebner K, Saldivar JC, Sun J, Shibata H, Druck T. Huebner K, et al. Among authors: sun j. Adv Enzyme Regul. 2011;51(1):208-17. doi: 10.1016/j.advenzreg.2010.09.003. Epub 2010 Oct 28. Adv Enzyme Regul. 2011. PMID: 21035495 Free PMC article. Review.
EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers.
Garofalo M, Romano G, Di Leva G, Nuovo G, Jeon YJ, Ngankeu A, Sun J, Lovat F, Alder H, Condorelli G, Engelman JA, Ono M, Rho JK, Cascione L, Volinia S, Nephew KP, Croce CM. Garofalo M, et al. Among authors: sun j. Nat Med. 2011 Dec 11;18(1):74-82. doi: 10.1038/nm.2577. Nat Med. 2011. PMID: 22157681 Free PMC article. Retracted.
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