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Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione.
Peracchi A, Veiga-da-Cunha M, Kuhara T, Ellens KW, Paczia N, Stroobant V, Seliga AK, Marlaire S, Jaisson S, Bommer GT, Sun J, Huebner K, Linster CL, Cooper AJL, Van Schaftingen E. Peracchi A, et al. Among authors: linster cl. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3233-E3242. doi: 10.1073/pnas.1613736114. Epub 2017 Apr 3. Proc Natl Acad Sci U S A. 2017. PMID: 28373563 Free PMC article.
Metabolite proofreading, a neglected aspect of intermediary metabolism.
Van Schaftingen E, Rzem R, Marbaix A, Collard F, Veiga-da-Cunha M, Linster CL. Van Schaftingen E, et al. Among authors: linster cl. J Inherit Metab Dis. 2013 May;36(3):427-34. doi: 10.1007/s10545-012-9571-1. Epub 2013 Jan 8. J Inherit Metab Dis. 2013. PMID: 23296366 Review.
Metabolite damage and its repair or pre-emption.
Linster CL, Van Schaftingen E, Hanson AD. Linster CL, et al. Nat Chem Biol. 2013 Feb;9(2):72-80. doi: 10.1038/nchembio.1141. Nat Chem Biol. 2013. PMID: 23334546 Review.
Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Michelucci A, Cordes T, Ghelfi J, Pailot A, Reiling N, Goldmann O, Binz T, Wegner A, Tallam A, Rausell A, Buttini M, Linster CL, Medina E, Balling R, Hiller K. Michelucci A, et al. Among authors: linster cl. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7820-5. doi: 10.1073/pnas.1218599110. Epub 2013 Apr 22. Proc Natl Acad Sci U S A. 2013. PMID: 23610393 Free PMC article.
48 results