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Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells.
Basit F, van Oppen LM, Schöckel L, Bossenbroek HM, van Emst-de Vries SE, Hermeling JC, Grefte S, Kopitz C, Heroult M, Hgm Willems P, Koopman WJ. Basit F, et al. Among authors: van emst de vries se. Cell Death Dis. 2017 Mar 30;8(3):e2716. doi: 10.1038/cddis.2017.133. Cell Death Dis. 2017. PMID: 28358377 Free PMC article.
Trolox-sensitive reactive oxygen species regulate mitochondrial morphology, oxidative phosphorylation and cytosolic calcium handling in healthy cells.
Distelmaier F, Valsecchi F, Forkink M, van Emst-de Vries S, Swarts HG, Rodenburg RJ, Verwiel ET, Smeitink JA, Willems PH, Koopman WJ. Distelmaier F, et al. Antioxid Redox Signal. 2012 Dec 15;17(12):1657-69. doi: 10.1089/ars.2011.4294. Epub 2012 Jun 13. Antioxid Redox Signal. 2012. PMID: 22559215 Free PMC article.
Corrigendum to "Mitigation of NADH:ubiquinone oxidoreductase deficiency by chronic Trolox treatment" [Biochimica et Biophysica Acta 1777/7-8 (2008) 853-859].
Koopman WJH, Verkaart S, van Emst-de Vries SE, Grefte S, Smeitink JAM, Nijtmans LGJ, Willems PHGM. Koopman WJH, et al. Among authors: van emst de vries se. Biochim Biophys Acta Bioenerg. 2018 Dec;1859(12):1328. doi: 10.1016/j.bbabio.2018.06.003. Epub 2018 Jun 6. Biochim Biophys Acta Bioenerg. 2018. PMID: 29883590 Free article. No abstract available.
The decylTPP mitochondria-targeting moiety lowers electron transport chain supercomplex levels in primary human skin fibroblasts.
Bulthuis EP, Einer C, Distelmaier F, Groh L, van Emst-de Vries SE, van de Westerlo E, van de Wal M, Wagenaars J, Rodenburg RJ, Smeitink JAM, Riksen NP, Willems PHGM, Adjobo-Hermans MJW, Zischka H, Koopman WJH. Bulthuis EP, et al. Among authors: van emst de vries se. Free Radic Biol Med. 2022 Aug 1;188:434-446. doi: 10.1016/j.freeradbiomed.2022.06.011. Epub 2022 Jun 17. Free Radic Biol Med. 2022. PMID: 35718301 Free article.
51 results