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A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens.
Sindhava VJ, Oropallo MA, Moody K, Naradikian M, Higdon LE, Zhou L, Myles A, Green N, Nündel K, Stohl W, Schmidt AM, Cao W, Dorta-Estremera S, Kambayashi T, Marshak-Rothstein A, Cancro MP. Sindhava VJ, et al. Among authors: schmidt am. J Clin Invest. 2017 May 1;127(5):1651-1663. doi: 10.1172/JCI89931. Epub 2017 Mar 27. J Clin Invest. 2017. PMID: 28346226 Free PMC article.
Regulatory T cells require TCR signaling for their suppressive function.
Schmidt AM, Lu W, Sindhava VJ, Huang Y, Burkhardt JK, Yang E, Riese MJ, Maltzman JS, Jordan MS, Kambayashi T. Schmidt AM, et al. J Immunol. 2015 May 1;194(9):4362-70. doi: 10.4049/jimmunol.1402384. Epub 2015 Mar 27. J Immunol. 2015. PMID: 25821220 Free PMC article.
TCR signaling intensity controls CD8+ T cell responsiveness to TGF-β.
Arumugam V, Bluemn T, Wesley E, Schmidt AM, Kambayashi T, Malarkannan S, Riese MJ. Arumugam V, et al. Among authors: schmidt am. J Leukoc Biol. 2015 Nov;98(5):703-12. doi: 10.1189/jlb.2HIMA1214-578R. Epub 2015 Jul 7. J Leukoc Biol. 2015. PMID: 26153417 Free PMC article.
691 results