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Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation.
Danquah W, Meyer-Schwesinger C, Rissiek B, Pinto C, Serracant-Prat A, Amadi M, Iacenda D, Knop JH, Hammel A, Bergmann P, Schwarz N, Assunção J, Rotthier W, Haag F, Tolosa E, Bannas P, Boué-Grabot E, Magnus T, Laeremans T, Stortelers C, Koch-Nolte F. Danquah W, et al. Among authors: hammel a. Sci Transl Med. 2016 Nov 23;8(366):366ra162. doi: 10.1126/scitranslmed.aaf8463. Sci Transl Med. 2016. PMID: 27881823
Ubiquitin C-Terminal Hydrolase L1 is required for regulated protein degradation through the ubiquitin proteasome system in kidney.
Radón V, Czesla M, Reichelt J, Fehlert J, Hammel A, Rosendahl A, Knop JH, Wiech T, Wenzel UO, Sachs M, Reinicke AT, Stahl RAK, Meyer-Schwesinger C. Radón V, et al. Among authors: hammel a. Kidney Int. 2018 Jan;93(1):110-127. doi: 10.1016/j.kint.2017.05.016. Epub 2017 Jul 26. Kidney Int. 2018. PMID: 28754552 Free article.
A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease.
Pelczar P, Witkowski M, Perez LG, Kempski J, Hammel AG, Brockmann L, Kleinschmidt D, Wende S, Haueis C, Bedke T, Witkowski M, Krasemann S, Steurer S, Booth CJ, Busch P, König A, Rauch U, Benten D, Izbicki JR, Rösch T, Lohse AW, Strowig T, Gagliani N, Flavell RA, Huber S. Pelczar P, et al. Among authors: hammel ag. Science. 2016 Oct 21;354(6310):358-362. doi: 10.1126/science.aah5903. Science. 2016. PMID: 27846573
14 results