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Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.
Moreno PM, Geny S, Pabon YV, Bergquist H, Zaghloul EM, Rocha CS, Oprea II, Bestas B, Andaloussi SE, Jørgensen PT, Pedersen EB, Lundin KE, Zain R, Wengel J, Smith CI. Moreno PM, et al. Among authors: zaghloul em. Nucleic Acids Res. 2013 Mar 1;41(5):3257-73. doi: 10.1093/nar/gkt007. Epub 2013 Jan 23. Nucleic Acids Res. 2013. PMID: 23345620 Free PMC article.
Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes.
Geny S, Moreno PM, Krzywkowski T, Gissberg O, Andersen NK, Isse AJ, El-Madani AM, Lou C, Pabon YV, Anderson BA, Zaghloul EM, Zain R, Hrdlicka PJ, Jørgensen PT, Nilsson M, Lundin KE, Pedersen EB, Wengel J, Smith CI. Geny S, et al. Among authors: zaghloul em. Nucleic Acids Res. 2016 Mar 18;44(5):2007-19. doi: 10.1093/nar/gkw021. Epub 2016 Feb 8. Nucleic Acids Res. 2016. PMID: 26857548 Free PMC article.
Nanotechnology approaches for gene transfer.
Lundin KE, Simonson OE, Moreno PM, Zaghloul EM, Oprea II, Svahn MG, Smith CI. Lundin KE, et al. Among authors: zaghloul em. Genetica. 2009 Sep;137(1):47-56. doi: 10.1007/s10709-009-9372-0. Epub 2009 Jun 2. Genetica. 2009. PMID: 19488829 Review.
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo.
Andaloussi SE, Lehto T, Mäger I, Rosenthal-Aizman K, Oprea II, Simonson OE, Sork H, Ezzat K, Copolovici DM, Kurrikoff K, Viola JR, Zaghloul EM, Sillard R, Johansson HJ, Said Hassane F, Guterstam P, Suhorutšenko J, Moreno PM, Oskolkov N, Hälldin J, Tedebark U, Metspalu A, Lebleu B, Lehtiö J, Smith CI, Langel U. Andaloussi SE, et al. Among authors: zaghloul em. Nucleic Acids Res. 2011 May;39(9):3972-87. doi: 10.1093/nar/gkq1299. Epub 2011 Jan 17. Nucleic Acids Res. 2011. PMID: 21245043 Free PMC article.
PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation.
Ezzat K, Andaloussi SE, Zaghloul EM, Lehto T, Lindberg S, Moreno PM, Viola JR, Magdy T, Abdo R, Guterstam P, Sillard R, Hammond SM, Wood MJ, Arzumanov AA, Gait MJ, Smith CI, Hällbrink M, Langel Ü. Ezzat K, et al. Among authors: zaghloul em. Nucleic Acids Res. 2011 Jul;39(12):5284-98. doi: 10.1093/nar/gkr072. Epub 2011 Feb 23. Nucleic Acids Res. 2011. PMID: 21345932 Free PMC article.
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