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Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.
Rubaiy HN, Ludlow MJ, Henrot M, Gaunt HJ, Miteva K, Cheung SY, Tanahashi Y, Hamzah N, Musialowski KE, Blythe NM, Appleby HL, Bailey MA, McKeown L, Taylor R, Foster R, Waldmann H, Nussbaumer P, Christmann M, Bon RS, Muraki K, Beech DJ. Rubaiy HN, et al. Among authors: beech dj. J Biol Chem. 2017 May 19;292(20):8158-8173. doi: 10.1074/jbc.M116.773556. Epub 2017 Mar 21. J Biol Chem. 2017. PMID: 28325835 Free PMC article.
TRPC1 store-operated cationic channel subunit.
Beech DJ, Xu SZ, McHugh D, Flemming R. Beech DJ, et al. Cell Calcium. 2003 May-Jun;33(5-6):433-40. doi: 10.1016/s0143-4160(03)00054-x. Cell Calcium. 2003. PMID: 12765688 Review.
TRPC1: store-operated channel and more.
Beech DJ. Beech DJ. Pflugers Arch. 2005 Oct;451(1):53-60. doi: 10.1007/s00424-005-1441-3. Epub 2005 Jun 18. Pflugers Arch. 2005. PMID: 15965706 Review.
Generation of functional ion-channel tools by E3 targeting.
Xu SZ, Zeng F, Lei M, Li J, Gao B, Xiong C, Sivaprasadarao A, Beech DJ. Xu SZ, et al. Among authors: beech dj. Nat Biotechnol. 2005 Oct;23(10):1289-93. doi: 10.1038/nbt1148. Epub 2005 Sep 18. Nat Biotechnol. 2005. PMID: 16170312
Sensing of lysophospholipids by TRPC5 calcium channel.
Flemming PK, Dedman AM, Xu SZ, Li J, Zeng F, Naylor J, Benham CD, Bateson AN, Muraki K, Beech DJ. Flemming PK, et al. Among authors: beech dj. J Biol Chem. 2006 Feb 24;281(8):4977-82. doi: 10.1074/jbc.M510301200. Epub 2005 Dec 20. J Biol Chem. 2006. PMID: 16368680 Free article.
256 results