Self-derived structure-disrupting peptides targeting methionine aminopeptidase in pathogenic bacteria: a new strategy to generate antimicrobial peptides.
Zhan J, Jia H, Semchenko EA, Bian Y, Zhou AM, Li Z, Yang Y, Wang J, Sarkar S, Totsika M, Blanchard H, Jen FE, Ye Q, Haselhorst T, Jennings MP, Seib KL, Zhou Y.
Zhan J, et al.
FASEB J. 2019 Feb;33(2):2095-2104. doi: 10.1096/fj.201700613RR. Epub 2018 Sep 27.
FASEB J. 2019.
PMID: 30260702
Free PMC article.
These findings present an exciting new paradigm in antibiotic discovery using self-derived peptides that can be developed to target the structures of any essential bacterial proteins.-Zhan, J., Jia, H., Semchenko, E. A., Bian, Y., Zhou, A. M., Li, Z., Yang, Y., Wang …
These findings present an exciting new paradigm in antibiotic discovery using self-derived peptides that can be developed to target the stru …