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Structure-activity profiles of complex biantennary glycans with core fucosylation and with/without additional alpha 2,3/alpha 2,6 sialylation: synthesis of neoglycoproteins and their properties in lectin assays, cell binding, and organ uptake.
Unverzagt C, André S, Seifert J, Kojima S, Fink C, Srikrishna G, Freeze H, Kayser K, Gabius HJ. Unverzagt C, et al. Among authors: kayser k. J Med Chem. 2002 Jan 17;45(2):478-91. doi: 10.1021/jm0110237. J Med Chem. 2002. PMID: 11784152
Determination of modulation of ligand properties of synthetic complex-type biantennary N-glycans by introduction of bisecting GlcNAc in silico, in vitro and in vivo.
André S, Unverzagt C, Kojima S, Frank M, Seifert J, Fink C, Kayser K, von der Lieth CW, Gabius HJ. André S, et al. Among authors: kayser k. Eur J Biochem. 2004 Jan;271(1):118-34. doi: 10.1046/j.1432-1033.2003.03910.x. Eur J Biochem. 2004. PMID: 14686925 Free article.
The panel of lectins, including an adhesion/growth-regulatory galectin, revealed up to a sixfold difference in affinity constants for these neoglycoproteins relative to data on the unsubstituted glycans reported previously [Andre, S., Unverzagt, C., Kojima, S., Dong, X., Fink, C. …
The panel of lectins, including an adhesion/growth-regulatory galectin, revealed up to a sixfold difference in affinity constants for these …
430 results