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Triheptanoin alters [U-13C6]-glucose incorporation into glycolytic intermediates and increases TCA cycling by normalizing the activities of pyruvate dehydrogenase and oxoglutarate dehydrogenase in a chronic epilepsy mouse model.
McDonald T, Hodson MP, Bederman I, Puchowicz M, Borges K. McDonald T, et al. J Cereb Blood Flow Metab. 2020 Mar;40(3):678-691. doi: 10.1177/0271678X19837380. Epub 2019 Mar 19. J Cereb Blood Flow Metab. 2020. PMID: 30890077 Free PMC article.
A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux.
Krokowski D, Han J, Saikia M, Majumder M, Yuan CL, Guan BJ, Bevilacqua E, Bussolati O, Bröer S, Arvan P, Tchórzewski M, Snider MD, Puchowicz M, Croniger CM, Kimball SR, Pan T, Koromilas AE, Kaufman RJ, Hatzoglou M. Krokowski D, et al. J Biol Chem. 2013 Jun 14;288(24):17202-13. doi: 10.1074/jbc.M113.466920. Epub 2013 May 3. J Biol Chem. 2013. PMID: 23645676 Free PMC article.
Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet.
Rutkowsky JM, Lee LL, Puchowicz M, Golub MS, Befroy DE, Wilson DW, Anderson S, Cline G, Bini J, Borkowski K, Knotts TA, Rutledge JC; Mouse Metabolic Phenotyping Center Imaging Working Group. Rutkowsky JM, et al. PLoS One. 2018 Feb 14;13(2):e0191909. doi: 10.1371/journal.pone.0191909. eCollection 2018. PLoS One. 2018. PMID: 29444171 Free PMC article.
Neuroprotective properties of ketone bodies.
Xu K, Lamanna JC, Puchowicz MA. Xu K, et al. Among authors: puchowicz ma. Adv Exp Med Biol. 2012;737:97-102. doi: 10.1007/978-1-4614-1566-4_15. Adv Exp Med Biol. 2012. PMID: 22259088 No abstract available.
91 results