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The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival.
Hardonnière K, Saunier E, Lemarié A, Fernier M, Gallais I, Héliès-Toussaint C, Mograbi B, Antonio S, Bénit P, Rustin P, Janin M, Habarou F, Ottolenghi C, Lavault MT, Benelli C, Sergent O, Huc L, Bortoli S, Lagadic-Gossmann D. Hardonnière K, et al. Among authors: gallais i. Sci Rep. 2016 Aug 4;6:30776. doi: 10.1038/srep30776. Sci Rep. 2016. PMID: 27488617 Free PMC article.
6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury.
Delehouzé C, Leverrier-Penna S, Le Cann F, Comte A, Jacquard-Fevai M, Delalande O, Desban N, Baratte B, Gallais I, Faurez F, Bonnet MC, Hauteville M, Goekjian PG, Thuillier R, Favreau F, Vandenabeele P, Hauet T, Dimanche-Boitrel MT, Bach S. Delehouzé C, et al. Among authors: gallais i. Sci Rep. 2017 Oct 10;7(1):12931. doi: 10.1038/s41598-017-12788-4. Sci Rep. 2017. PMID: 29018243 Free PMC article.
Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide.
Tête A, Gallais I, Imran M, Chevanne M, Liamin M, Sparfel L, Bucher S, Burel A, Podechard N, Appenzeller BMR, Fromenty B, Grova N, Sergent O, Lagadic-Gossmann D. Tête A, et al. Among authors: gallais i. Free Radic Biol Med. 2018 Dec;129:323-337. doi: 10.1016/j.freeradbiomed.2018.09.042. Epub 2018 Sep 27. Free Radic Biol Med. 2018. PMID: 30268890 Free article.
Polycyclic Aromatic Hydrocarbons Can Trigger Hepatocyte Release of Extracellular Vesicles by Various Mechanisms of Action Depending on Their Affinity for the Aryl Hydrocarbon Receptor.
van Meteren N, Lagadic-Gossmann D, Chevanne M, Gallais I, Gobart D, Burel A, Bucher S, Grova N, Fromenty B, Appenzeller BMR, Chevance S, Gauffre F, Le Ferrec E, Sergent O. van Meteren N, et al. Among authors: gallais i. Toxicol Sci. 2019 Oct 1;171(2):443-462. doi: 10.1093/toxsci/kfz157. Toxicol Sci. 2019. PMID: 31368503
Extracellular vesicles released by polycyclic aromatic hydrocarbons-treated hepatocytes trigger oxidative stress in recipient hepatocytes by delivering iron.
van Meteren N, Lagadic-Gossmann D, Podechard N, Gobart D, Gallais I, Chevanne M, Collin A, Burel A, Dupont A, Rault L, Chevance S, Gauffre F, Le Ferrec E, Sergent O. van Meteren N, et al. Among authors: gallais i. Free Radic Biol Med. 2020 Nov 20;160:246-262. doi: 10.1016/j.freeradbiomed.2020.08.001. Epub 2020 Aug 10. Free Radic Biol Med. 2020. PMID: 32791186 Free article.
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