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Protein misfolding in neurodegenerative diseases: implications and strategies.
Sweeney P, Park H, Baumann M, Dunlop J, Frydman J, Kopito R, McCampbell A, Leblanc G, Venkateswaran A, Nurmi A, Hodgson R. Sweeney P, et al. Among authors: nurmi a. Transl Neurodegener. 2017 Mar 13;6:6. doi: 10.1186/s40035-017-0077-5. eCollection 2017. Transl Neurodegener. 2017. PMID: 28293421 Free PMC article. Review.
Cognitive disturbances in the cuprizone model of multiple sclerosis.
Kopanitsa MV, Lehtimäki KK, Forsman M, Suhonen A, Koponen J, Piiponniemi TO, Kärkkäinen AM, Pavlidi P, Shatillo A, Sweeney PJ, Merenlender-Wagner A, Kaye J, Orbach A, Nurmi A. Kopanitsa MV, et al. Among authors: nurmi a. Genes Brain Behav. 2021 Jan;20(1):e12663. doi: 10.1111/gbb.12663. Epub 2020 May 25. Genes Brain Behav. 2021. PMID: 32372528 Free article.
A multimodal approach to identify clinically relevant biomarkers to comprehensively monitor disease progression in a mouse model of pediatric neurodegenerative disease.
Johnson TB, Brudvig JJ, Lehtimäki KK, Cain JT, White KA, Bragge T, Rytkönen J, Huhtala T, Timm D, Vihma M, Puoliväli JT, Poutiainen P, Nurmi A, Weimer JM. Johnson TB, et al. Among authors: nurmi a. Prog Neurobiol. 2020 Jun;189:101789. doi: 10.1016/j.pneurobio.2020.101789. Epub 2020 Mar 18. Prog Neurobiol. 2020. PMID: 32198061
The radical scavenger IAC (bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) decantionate) decreases mortality, enhances cognitive functions in water maze and reduces amyloid plaque burden in hAβPP transgenic mice.
Puoliväli J, Nurmi A, Miettinen TK, Soleti A, Riccardino F, Kalesnykas G, Heikkinen T, Vartiainen N, Pussinen R, Tähtivaara L, Lehtimäki K, Yrjänheikki J, Canistro D, Sapone A, Spisni E, Paolini M. Puoliväli J, et al. Among authors: nurmi a. J Alzheimers Dis. 2011;27(3):499-510. doi: 10.3233/JAD-2011-110881. J Alzheimers Dis. 2011. PMID: 21821875
Alteration of prolyl oligopeptidase and activated α-2-macroglobulin in multiple sclerosis subtypes and in the clinically isolated syndrome.
Tenorio-Laranga J, Peltonen I, Keskitalo S, Duran-Torres G, Natarajan R, Männistö PT, Nurmi A, Vartiainen N, Airas L, Elovaara I, García-Horsman JA. Tenorio-Laranga J, et al. Among authors: nurmi a. Biochem Pharmacol. 2013 Jun 15;85(12):1783-94. doi: 10.1016/j.bcp.2013.04.018. Epub 2013 Apr 30. Biochem Pharmacol. 2013. PMID: 23643808
61 results