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Regulatory T cells promote myelin regeneration in the central nervous system.
Dombrowski Y, O'Hagan T, Dittmer M, Penalva R, Mayoral SR, Bankhead P, Fleville S, Eleftheriadis G, Zhao C, Naughton M, Hassan R, Moffat J, Falconer J, Boyd A, Hamilton P, Allen IV, Kissenpfennig A, Moynagh PN, Evergren E, Perbal B, Williams AC, Ingram RJ, Chan JR, Franklin RJM, Fitzgerald DC. Dombrowski Y, et al. Among authors: zhao c. Nat Neurosci. 2017 May;20(5):674-680. doi: 10.1038/nn.4528. Epub 2017 Mar 13. Nat Neurosci. 2017. PMID: 28288125 Free PMC article.
Depletion of endogenous oligodendrocyte progenitors rather than increased availability of survival factors is a likely explanation for enhanced survival of transplanted oligodendrocyte progenitors in X-irradiated compared to normal CNS.
Hinks GL, Chari DM, O'Leary MT, Zhao C, Keirstead HS, Blakemore WF, Franklin RJ. Hinks GL, et al. Among authors: zhao c. Neuropathol Appl Neurobiol. 2001 Feb;27(1):59-67. doi: 10.1046/j.0305-1846.2001.00303.x. Neuropathol Appl Neurobiol. 2001. PMID: 11299003
Ageing and CNS remyelination.
Franklin RJ, Zhao C, Sim FJ. Franklin RJ, et al. Among authors: zhao c. Neuroreport. 2002 May 24;13(7):923-8. doi: 10.1097/00001756-200205240-00001. Neuroreport. 2002. PMID: 12004191 Review.
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