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Bug mapping and fitness testing of chemically synthesized chromosome X.
Wu Y, Li BZ, Zhao M, Mitchell LA, Xie ZX, Lin QH, Wang X, Xiao WH, Wang Y, Zhou X, Liu H, Li X, Ding MZ, Liu D, Zhang L, Liu BL, Wu XL, Li FF, Dong XT, Jia B, Zhang WZ, Jiang GZ, Liu Y, Bai X, Song TQ, Chen Y, Zhou SJ, Zhu RY, Gao F, Kuang Z, Wang X, Shen M, Yang K, Stracquadanio G, Richardson SM, Lin Y, Wang L, Walker R, Luo Y, Ma PS, Yang H, Cai Y, Dai J, Bader JS, Boeke JD, Yuan YJ. Wu Y, et al. Among authors: shen m. Science. 2017 Mar 10;355(6329):eaaf4706. doi: 10.1126/science.aaf4706. Science. 2017. PMID: 28280152 Free PMC article.
3D organization of synthetic and scrambled chromosomes.
Mercy G, Mozziconacci J, Scolari VF, Yang K, Zhao G, Thierry A, Luo Y, Mitchell LA, Shen M, Shen Y, Walker R, Zhang W, Wu Y, Xie ZX, Luo Z, Cai Y, Dai J, Yang H, Yuan YJ, Boeke JD, Bader JS, Muller H, Koszul R. Mercy G, et al. Among authors: shen y, shen m. Science. 2017 Mar 10;355(6329):eaaf4597. doi: 10.1126/science.aaf4597. Science. 2017. PMID: 28280150 Free PMC article.
Precise control of SCRaMbLE in synthetic haploid and diploid yeast.
Jia B, Wu Y, Li BZ, Mitchell LA, Liu H, Pan S, Wang J, Zhang HR, Jia N, Li B, Shen M, Xie ZX, Liu D, Cao YX, Li X, Zhou X, Qi H, Boeke JD, Yuan YJ. Jia B, et al. Among authors: shen m. Nat Commun. 2018 May 22;9(1):1933. doi: 10.1038/s41467-018-03084-4. Nat Commun. 2018. PMID: 29789567 Free PMC article.
Heterozygous diploid and interspecies SCRaMbLEing.
Shen MJ, Wu Y, Yang K, Li Y, Xu H, Zhang H, Li BZ, Li X, Xiao WH, Zhou X, Mitchell LA, Bader JS, Yuan Y, Boeke JD. Shen MJ, et al. Nat Commun. 2018 May 22;9(1):1934. doi: 10.1038/s41467-018-04157-0. Nat Commun. 2018. PMID: 29789590 Free PMC article.
Alternative splicing is a developmental switch for hTERT expression.
Penev A, Bazley A, Shen M, Boeke JD, Savage SA, Sfeir A. Penev A, et al. Among authors: shen m. Mol Cell. 2021 Jun 3;81(11):2349-2360.e6. doi: 10.1016/j.molcel.2021.03.033. Epub 2021 Apr 13. Mol Cell. 2021. PMID: 33852895 Free PMC article.
Resurrecting essential amino acid biosynthesis in mammalian cells.
Trolle J, McBee RM, Kaufman A, Pinglay S, Berger H, German S, Liu L, Shen MJ, Guo X, Martin JA, Pacold ME, Jones DR, Boeke JD, Wang HH. Trolle J, et al. Among authors: shen mj. Elife. 2022 Sep 27;11:e72847. doi: 10.7554/eLife.72847. Elife. 2022. PMID: 36165439 Free PMC article.
Manipulating the 3D organization of the largest synthetic yeast chromosome.
Zhang W, Lazar-Stefanita L, Yamashita H, Shen MJ, Mitchell LA, Kurasawa H, Lobzaev E, Fanfani V, Haase MAB, Sun X, Jiang Q, Goldberg GW, Ichikawa DM, Lauer SL, McCulloch LH, Easo N, Lin SJ, Camellato BR, Zhu Y, Cai J, Xu Z, Zhao Y, Sacasa M; Build-A-Genome Class; Noyes MB, Bader JS, Deutsch S, Stracquadanio G, Aizawa Y, Dai J, Boeke JD. Zhang W, et al. Among authors: shen mj. Mol Cell. 2023 Dec 7;83(23):4424-4437.e5. doi: 10.1016/j.molcel.2023.10.015. Epub 2023 Nov 8. Mol Cell. 2023. PMID: 37944526 Free article.
6,484 results