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Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid: a pragmatic, non-inferiority, randomised controlled trial.
Williams HC, Wojnarowska F, Kirtschig G, Mason J, Godec TR, Schmidt E, Chalmers JR, Childs M, Walton S, Harman K, Chapman A, Whitham D, Nunn AJ; UK Dermatology Clinical Trials Network BLISTER Study Group. Williams HC, et al. Among authors: nunn aj. Lancet. 2017 Apr 22;389(10079):1630-1638. doi: 10.1016/S0140-6736(17)30560-3. Epub 2017 Mar 6. Lancet. 2017. PMID: 28279484 Free PMC article. Clinical Trial.
Penicillin to prevent recurrent leg cellulitis.
Thomas KS, Crook AM, Nunn AJ, Foster KA, Mason JM, Chalmers JR, Nasr IS, Brindle RJ, English J, Meredith SK, Reynolds NJ, de Berker D, Mortimer PS, Williams HC; U.K. Dermatology Clinical Trials Network's PATCH I Trial Team. Thomas KS, et al. Among authors: nunn aj. N Engl J Med. 2013 May 2;368(18):1695-703. doi: 10.1056/NEJMoa1206300. N Engl J Med. 2013. PMID: 23635049 Free article. Clinical Trial.
Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): a 12-month, multicentre, randomised trial.
McMillan A, Bratton DJ, Faria R, Laskawiec-Szkonter M, Griffin S, Davies RJ, Nunn AJ, Stradling JR, Riha RL, Morrell MJ; PREDICT Investigators. McMillan A, et al. Among authors: nunn aj. Lancet Respir Med. 2014 Oct;2(10):804-12. doi: 10.1016/S2213-2600(14)70172-9. Epub 2014 Aug 26. Lancet Respir Med. 2014. PMID: 25172769 Free article. Clinical Trial.
What is a pragmatic clinical trial?
Williams HC, Burden-Teh E, Nunn AJ. Williams HC, et al. Among authors: nunn aj. J Invest Dermatol. 2015 Jun;135(6):1-3. doi: 10.1038/jid.2015.134. J Invest Dermatol. 2015. PMID: 25964272 Free article. No abstract available.
A randomised controlled trial to compare the safety, effectiveness and cost-effectiveness of doxycycline (200 mg/day) with that of oral prednisolone (0.5 mg/kg/day) for initial treatment of bullous pemphigoid: the Bullous Pemphigoid Steroids and Tetracyclines (BLISTER) trial.
Chalmers JR, Wojnarowska F, Kirtschig G, Mason J, Childs M, Whitham D, Harman K, Chapman A, Walton S, Schmidt E, Godec TR, Nunn AJ, Williams HC. Chalmers JR, et al. Among authors: nunn aj. Health Technol Assess. 2017 Mar;21(10):1-90. doi: 10.3310/hta21100. Health Technol Assess. 2017. PMID: 28406394 Free PMC article. Clinical Trial.
The ethics of non-inferiority trials.
Nunn AJ, Meredith SK, Spigelman MK, Ginsberg AM, Gillespie SH. Nunn AJ, et al. Lancet. 2008 Mar 15;371(9616):895; author reply 896-7. doi: 10.1016/S0140-6736(08)60404-3. Lancet. 2008. PMID: 18342678 No abstract available.
254 results