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Novel hydroxamates potentiated in vitro activity of fluconazole against Candida albicans.
Paul-Satyaseela M, Hariharan P, Bharani T, Franklyne JS, Selvakumar T, Bharathimohan K, Kumar CV, Kachhadia V, Narayanan S, Rajagopal S, Balasubramanian G. Paul-Satyaseela M, et al. Among authors: narayanan s. J Nat Sci Biol Med. 2017 Jan-Jun;8(1):119-124. doi: 10.4103/0976-9668.198349. J Nat Sci Biol Med. 2017. PMID: 28250687 Free PMC article.
Functional characterization of Candida albicans Hos2 histone deacetylase.
Karthikeyan G, Paul-Satyaseela M, Dhatchana Moorthy N, Gopalaswamy R, Narayanan S. Karthikeyan G, et al. Among authors: narayanan s. F1000Res. 2013 Nov 11;2:238. doi: 10.12688/f1000research.2-238.v3. eCollection 2013. F1000Res. 2013. PMID: 25110576 Free PMC article.
Discovery of adamantane based highly potent HDAC inhibitors.
Gopalan B, Ponpandian T, Kachhadia V, Bharathimohan K, Vignesh R, Sivasudar V, Narayanan S, Mandar B, Praveen R, Saranya N, Rajagopal S, Rajagopal S. Gopalan B, et al. Among authors: narayanan s. Bioorg Med Chem Lett. 2013 May 1;23(9):2532-7. doi: 10.1016/j.bmcl.2013.03.002. Epub 2013 Mar 14. Bioorg Med Chem Lett. 2013. PMID: 23538115
Orally available stilbene derivatives as potent HDAC inhibitors with antiproliferative activities and antitumor effects in human tumor xenografts.
Kachhadia V, Rajagopal S, Ponpandian T, Vignesh R, Anandhan K, Prabhu D, Rajendran P, Nidhyanandan S, Roy AM, Ahamed FA, Surendran N, Rajagopal S, Narayanan S, Gopalan B. Kachhadia V, et al. Among authors: narayanan s. Eur J Med Chem. 2016 Jan 27;108:274-286. doi: 10.1016/j.ejmech.2015.11.014. Epub 2015 Nov 19. Eur J Med Chem. 2016. PMID: 26689485
Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects.
Vishwakarma S, Iyer LR, Muley M, Singh PK, Shastry A, Saxena A, Kulathingal J, Vijaykanth G, Raghul J, Rajesh N, Rathinasamy S, Kachhadia V, Kilambi N, Rajgopal S, Balasubramanian G, Narayanan S. Vishwakarma S, et al. Among authors: narayanan s. Int Immunopharmacol. 2013 May;16(1):72-8. doi: 10.1016/j.intimp.2013.03.016. Epub 2013 Mar 27. Int Immunopharmacol. 2013. PMID: 23541634
In vivo effective dibenzo[b,d]furan-1-yl-thiazoles as novel PDE-4 inhibitors.
Balasubramanian G, Narayanan S, Andiappan L, Sappanimuthu T, Thirunavukkarasu S, Sundaram S, Natarajan S, Sivaraman N, Rajagopal S, Nazumudeen FAA, Saxena S, Vishwakarma SL, Narayanan S, Sharma GVR, Srinivasan CV, Kilambi N. Balasubramanian G, et al. Among authors: narayanan s. Bioorg Med Chem. 2016 Nov 15;24(22):5702-5716. doi: 10.1016/j.bmc.2016.09.011. Epub 2016 Sep 9. Bioorg Med Chem. 2016. PMID: 27713015
Quinolone-based HDAC inhibitors.
Balasubramanian G, Kilambi N, Rathinasamy S, Rajendran P, Narayanan S, Rajagopal S. Balasubramanian G, et al. Among authors: narayanan s. J Enzyme Inhib Med Chem. 2014 Aug;29(4):555-62. doi: 10.3109/14756366.2013.827675. Epub 2013 Sep 9. J Enzyme Inhib Med Chem. 2014. PMID: 25019596
1,994 results