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Novel hydroxamates potentiated in vitro activity of fluconazole against Candida albicans.
Paul-Satyaseela M, Hariharan P, Bharani T, Franklyne JS, Selvakumar T, Bharathimohan K, Kumar CV, Kachhadia V, Narayanan S, Rajagopal S, Balasubramanian G. Paul-Satyaseela M, et al. Among authors: kachhadia v. J Nat Sci Biol Med. 2017 Jan-Jun;8(1):119-124. doi: 10.4103/0976-9668.198349. J Nat Sci Biol Med. 2017. PMID: 28250687 Free PMC article.
Discovery of adamantane based highly potent HDAC inhibitors.
Gopalan B, Ponpandian T, Kachhadia V, Bharathimohan K, Vignesh R, Sivasudar V, Narayanan S, Mandar B, Praveen R, Saranya N, Rajagopal S, Rajagopal S. Gopalan B, et al. Among authors: kachhadia v. Bioorg Med Chem Lett. 2013 May 1;23(9):2532-7. doi: 10.1016/j.bmcl.2013.03.002. Epub 2013 Mar 14. Bioorg Med Chem Lett. 2013. PMID: 23538115
Orally available stilbene derivatives as potent HDAC inhibitors with antiproliferative activities and antitumor effects in human tumor xenografts.
Kachhadia V, Rajagopal S, Ponpandian T, Vignesh R, Anandhan K, Prabhu D, Rajendran P, Nidhyanandan S, Roy AM, Ahamed FA, Surendran N, Rajagopal S, Narayanan S, Gopalan B. Kachhadia V, et al. Eur J Med Chem. 2016 Jan 27;108:274-286. doi: 10.1016/j.ejmech.2015.11.014. Epub 2015 Nov 19. Eur J Med Chem. 2016. PMID: 26689485
Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects.
Vishwakarma S, Iyer LR, Muley M, Singh PK, Shastry A, Saxena A, Kulathingal J, Vijaykanth G, Raghul J, Rajesh N, Rathinasamy S, Kachhadia V, Kilambi N, Rajgopal S, Balasubramanian G, Narayanan S. Vishwakarma S, et al. Among authors: kachhadia v. Int Immunopharmacol. 2013 May;16(1):72-8. doi: 10.1016/j.intimp.2013.03.016. Epub 2013 Mar 27. Int Immunopharmacol. 2013. PMID: 23541634