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Longitudinal soluble marker profiles reveal strong association between cytokine storms resulting from macrophage activation and disease severity in COVID-19 disease.
van Meijgaarden KE, van Veen S, Tsonaka R, Ruibal P, Roukens AHE, Arbous SM, Manniën J, Cannegieter SC, Ottenhoff THM, Joosten SA; BEAT-COVID group; COVID-19 LUMC group. van Meijgaarden KE, et al. Among authors: joosten sa. Sci Rep. 2024 Jun 5;14(1):12882. doi: 10.1038/s41598-024-63586-8. Sci Rep. 2024. PMID: 38839796
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions.
Joosten SEP, Gregoricchio S, Stelloo S, Yapıcı E, Huang CF, Yavuz K, Donaldson Collier M, Morova T, Altintaş UB, Kim Y, Canisius S, Moelans CB, van Diest PJ, Korkmaz G, Lack NA, Vermeulen M, Linn SC, Zwart W. Joosten SEP, et al. Genome Res. 2024 May 15;34(4):539-555. doi: 10.1101/gr.278680.123. Genome Res. 2024. PMID: 38719469
Mtb HLA-E-tetramer-sorted CD8+ T cells have a diverse TCR repertoire.
Voogd L, Drittij AMHF, Dingenouts CKE, Franken KLMC, Unen VV, van Meijgaarden KE, Ruibal P, Hagedoorn RS, Leitner JA, Steinberger P, Heemskerk MHM, Davis MM, Scriba TJ, Ottenhoff THM, Joosten SA. Voogd L, et al. Among authors: joosten sa. iScience. 2024 Feb 15;27(3):109233. doi: 10.1016/j.isci.2024.109233. eCollection 2024 Mar 15. iScience. 2024. PMID: 38439958 Free PMC article.
Lymphopenia is associated with broad host response aberrations in community-acquired pneumonia.
Doeleman SE, Reijnders TDY, Joosten SCM, Schuurman AR, van Engelen TSR, Verhoeff J, Léopold V, Brands X, Haak BW, Prins JM, Kanglie MMNP, van den Berk IAH, Faber DR, Douma RA, Stoker J, Saris A, Garcia Vallejo JJ, Wiersinga WJ, van der Poll T. Doeleman SE, et al. Among authors: joosten scm. J Infect. 2024 Apr;88(4):106131. doi: 10.1016/j.jinf.2024.106131. Epub 2024 Feb 29. J Infect. 2024. PMID: 38431153 Free article.
The shifting lipidomic landscape of blood monocytes and neutrophils during pneumonia.
Schuurman AR, Chouchane O, Butler JM, Peters-Sengers H, Joosten S, Brands X, Haak BW, Otto NA, Uhel F, Klarenbeek A, van Linge CC, van Kampen A, Pras-Raves M, van Weeghel M, van Eijk M, Ferraz MJ, Faber DR, de Vos A, Scicluna BP, Vaz FM, Wiersinga WJ, van der Poll T. Schuurman AR, et al. Among authors: joosten s. JCI Insight. 2024 Feb 22;9(4):e164400. doi: 10.1172/jci.insight.164400. JCI Insight. 2024. PMID: 38385743 Free PMC article.
262 results