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Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1.
Shabalina IG, Vyssokikh MY, Gibanova N, Csikasz RI, Edgar D, Hallden-Waldemarson A, Rozhdestvenskaya Z, Bakeeva LE, Vays VB, Pustovidko AV, Skulachev MV, Cannon B, Skulachev VP, Nedergaard J. Shabalina IG, et al. Among authors: bakeeva le. Aging (Albany NY). 2017 Feb 15;9(2):315-339. doi: 10.18632/aging.101174. Aging (Albany NY). 2017. PMID: 28209927 Free PMC article.
Progressive reorganization of mitochondrial apparatus in aging skeletal muscle of naked mole rats (Heterocephalus glaber) as revealed by electron microscopy: potential role in continual maintenance of muscle activity.
Vays V, Vangely I, Eldarov C, Holtze S, Hildebrandt T, Bakeeva L, Skulachev V. Vays V, et al. Aging (Albany NY). 2021 Nov 28;13(22):24524-24541. doi: 10.18632/aging.203720. Epub 2021 Nov 28. Aging (Albany NY). 2021. PMID: 34839281 Free PMC article.
An attempt to prevent senescence: a mitochondrial approach.
Skulachev VP, Anisimov VN, Antonenko YN, Bakeeva LE, Chernyak BV, Erichev VP, Filenko OF, Kalinina NI, Kapelko VI, Kolosova NG, Kopnin BP, Korshunova GA, Lichinitser MR, Obukhova LA, Pasyukova EG, Pisarenko OI, Roginsky VA, Ruuge EK, Senin II, Severina II, Skulachev MV, Spivak IM, Tashlitsky VN, Tkachuk VA, Vyssokikh MY, Yaguzhinsky LS, Zorov DB. Skulachev VP, et al. Among authors: bakeeva le. Biochim Biophys Acta. 2009 May;1787(5):437-61. doi: 10.1016/j.bbabio.2008.12.008. Epub 2008 Dec 29. Biochim Biophys Acta. 2009. PMID: 19159610 Free article. Review.
Neoteny, Prolongation of Youth: From Naked Mole Rats to "Naked Apes" (Humans).
Skulachev VP, Holtze S, Vyssokikh MY, Bakeeva LE, Skulachev MV, Markov AV, Hildebrandt TB, Sadovnichii VA. Skulachev VP, et al. Among authors: bakeeva le. Physiol Rev. 2017 Apr;97(2):699-720. doi: 10.1152/physrev.00040.2015. Physiol Rev. 2017. PMID: 28202600 Free article. Review.
Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: synthesis and in vitro studies.
Antonenko YN, Avetisyan AV, Bakeeva LE, Chernyak BV, Chertkov VA, Domnina LV, Ivanova OY, Izyumov DS, Khailova LS, Klishin SS, Korshunova GA, Lyamzaev KG, Muntyan MS, Nepryakhina OK, Pashkovskaya AA, Pletjushkina OY, Pustovidko AV, Roginsky VA, Rokitskaya TI, Ruuge EK, Saprunova VB, Severina II, Simonyan RA, Skulachev IV, Skulachev MV, Sumbatyan NV, Sviryaeva IV, Tashlitsky VN, Vassiliev JM, Vyssokikh MY, Yaguzhinsky LS, Zamyatnin AA Jr, Skulachev VP. Antonenko YN, et al. Among authors: bakeeva le. Biochemistry (Mosc). 2008 Dec;73(12):1273-87. doi: 10.1134/s0006297908120018. Biochemistry (Mosc). 2008. PMID: 19120014 Free article.
Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 2. Treatment of some ROS- and age-related diseases (heart arrhythmia, heart infarctions, kidney ischemia, and stroke).
Bakeeva LE, Barskov IV, Egorov MV, Isaev NK, Kapelko VI, Kazachenko AV, Kirpatovsky VI, Kozlovsky SV, Lakomkin VL, Levina SB, Pisarenko OI, Plotnikov EY, Saprunova VB, Serebryakova LI, Skulachev MV, Stelmashook EV, Studneva IM, Tskitishvili OV, Vasilyeva AK, Victorov IV, Zorov DB, Skulachev VP. Bakeeva LE, et al. Biochemistry (Mosc). 2008 Dec;73(12):1288-99. doi: 10.1134/s000629790812002x. Biochemistry (Mosc). 2008. PMID: 19120015 Free article.
Novel mechanism of elimination of malfunctioning mitochondria (mitoptosis): formation of mitoptotic bodies and extrusion of mitochondrial material from the cell.
Lyamzaev KG, Nepryakhina OK, Saprunova VB, Bakeeva LE, Pletjushkina OY, Chernyak BV, Skulachev VP. Lyamzaev KG, et al. Among authors: bakeeva le. Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):817-25. doi: 10.1016/j.bbabio.2008.03.027. Epub 2008 Apr 8. Biochim Biophys Acta. 2008. PMID: 18433711 Free article.
75 results