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Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice.
Science. 2017 Feb 17;355(6326):756-760. doi: 10.1126/science.aal0092.
Science. 2017.
PMID: 28209901
Free PMC article.
GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma.
Williams PA, Braine CE, Foxworth NE, Cochran KE, John SWM.
Williams PA, et al. Among authors: foxworth ne.
J Neuroinflammation. 2017 Apr 26;14(1):93. doi: 10.1186/s12974-017-0868-8.
J Neuroinflammation. 2017.
PMID: 28446179
Free PMC article.
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Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma.
Williams PA, Harder JM, Foxworth NE, Cardozo BH, Cochran KE, John SWM.
Williams PA, et al. Among authors: foxworth ne.
Front Neurosci. 2017 Apr 25;11:232. doi: 10.3389/fnins.2017.00232. eCollection 2017.
Front Neurosci. 2017.
PMID: 28487632
Free PMC article.
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Nicotinamide treatment robustly protects from inherited mouse glaucoma.
Williams PA, Harder JM, Cardozo BH, Foxworth NE, John SWM.
Williams PA, et al. Among authors: foxworth ne.
Commun Integr Biol. 2018 Jan 19;11(1):e1356956. doi: 10.1080/19420889.2017.1356956. eCollection 2018.
Commun Integr Biol. 2018.
PMID: 29497468
Free PMC article.
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Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice.
Harder JM, Williams PA, Soto I, Foxworth NE, Fernandes KA, Freeburg NF, Libby RT, John SWM.
Harder JM, et al. Among authors: foxworth ne.
Cell Death Dis. 2018 Jun 13;9(6):705. doi: 10.1038/s41419-018-0705-8.
Cell Death Dis. 2018.
PMID: 29899326
Free PMC article.
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Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma.
Williams PA, Braine CE, Kizhatil K, Foxworth NE, Tolman NG, Harder JM, Scott RA, Sousa GL, Panitch A, Howell GR, John SWM.
Williams PA, et al. Among authors: foxworth ne.
Mol Neurodegener. 2019 Jan 22;14(1):6. doi: 10.1186/s13024-018-0303-3.
Mol Neurodegener. 2019.
PMID: 30670050
Free PMC article.
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Complement peptide C3a receptor 1 promotes optic nerve degeneration in DBA/2J mice.
Harder JM, Williams PA, Braine CE, Yang HS, Thomas JM, Foxworth NE, John SWM, Howell GR.
Harder JM, et al. Among authors: foxworth ne.
J Neuroinflammation. 2020 Nov 11;17(1):336. doi: 10.1186/s12974-020-02011-z.
J Neuroinflammation. 2020.
PMID: 33176797
Free PMC article.
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Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin.
Harder JM, Guymer C, Wood JPM, Daskalaki E, Chidlow G, Zhang C, Balasubramanian R, Cardozo BH, Foxworth NE, Deering KE, Ouellette TB, Montgomery C, Wheelock CE, Casson RJ, Williams PA, John SWM.
Harder JM, et al. Among authors: foxworth ne.
Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33619-33627. doi: 10.1073/pnas.2014213117. Epub 2020 Dec 14.
Proc Natl Acad Sci U S A. 2020.
PMID: 33318177
Free PMC article.
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