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Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes.
Chen Z, Xian W, Bellin M, Dorn T, Tian Q, Goedel A, Dreizehnter L, Schneider CM, Ward-van Oostwaard D, Ng JK, Hinkel R, Pane LS, Mummery CL, Lipp P, Moretti A, Laugwitz KL, Sinnecker D. Chen Z, et al. Among authors: dreizehnter l. Eur Heart J. 2017 Jan 21;38(4):292-301. doi: 10.1093/eurheartj/ehw189. Eur Heart J. 2017. PMID: 28182242 Free PMC article.
Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Rocchetti M, Sala L, Dreizehnter L, Crotti L, Sinnecker D, Mura M, Pane LS, Altomare C, Torre E, Mostacciuolo G, Severi S, Porta A, De Ferrari GM, George AL Jr, Schwartz PJ, Gnecchi M, Moretti A, Zaza A. Rocchetti M, et al. Among authors: dreizehnter l. Cardiovasc Res. 2017 Apr 1;113(5):531-541. doi: 10.1093/cvr/cvx006. Cardiovasc Res. 2017. PMID: 28158429
Suppression of Arrhythmia by Enhancing Mitochondrial Ca2+ Uptake in Catecholaminergic Ventricular Tachycardia Models.
Schweitzer MK, Wilting F, Sedej S, Dreizehnter L, Dupper NJ, Tian Q, Moretti A, My I, Kwon O, Priori SG, Laugwitz KL, Storch U, Lipp P, Breit A, Mederos Y Schnitzler M, Gudermann T, Schredelseker J. Schweitzer MK, et al. Among authors: dreizehnter l. JACC Basic Transl Sci. 2017 Dec;2(6):737-747. doi: 10.1016/j.jacbts.2017.06.008. Epub 2017 Nov 8. JACC Basic Transl Sci. 2017. PMID: 29354781 Free PMC article.
Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.
van den Boogaard M, Wong LY, Tessadori F, Bakker ML, Dreizehnter LK, Wakker V, Bezzina CR, 't Hoen PA, Bakkers J, Barnett P, Christoffels VM. van den Boogaard M, et al. Among authors: dreizehnter lk. J Clin Invest. 2012 Jul;122(7):2519-30. doi: 10.1172/JCI62613. Epub 2012 Jun 18. J Clin Invest. 2012. PMID: 22706305 Free PMC article.