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Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes.
Eur Heart J. 2017 Jan 21;38(4):292-301. doi: 10.1093/eurheartj/ehw189.
Eur Heart J. 2017.
PMID: 28182242
Free PMC article.
Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Rocchetti M, Sala L, Dreizehnter L, Crotti L, Sinnecker D, Mura M, Pane LS, Altomare C, Torre E, Mostacciuolo G, Severi S, Porta A, De Ferrari GM, George AL Jr, Schwartz PJ, Gnecchi M, Moretti A, Zaza A.
Rocchetti M, et al. Among authors: dreizehnter l.
Cardiovasc Res. 2017 Apr 1;113(5):531-541. doi: 10.1093/cvr/cvx006.
Cardiovasc Res. 2017.
PMID: 28158429
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Suppression of Arrhythmia by Enhancing Mitochondrial Ca2+ Uptake in Catecholaminergic Ventricular Tachycardia Models.
Schweitzer MK, Wilting F, Sedej S, Dreizehnter L, Dupper NJ, Tian Q, Moretti A, My I, Kwon O, Priori SG, Laugwitz KL, Storch U, Lipp P, Breit A, Mederos Y Schnitzler M, Gudermann T, Schredelseker J.
Schweitzer MK, et al. Among authors: dreizehnter l.
JACC Basic Transl Sci. 2017 Dec;2(6):737-747. doi: 10.1016/j.jacbts.2017.06.008. Epub 2017 Nov 8.
JACC Basic Transl Sci. 2017.
PMID: 29354781
Free PMC article.
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Approved drugs ezetimibe and disulfiram enhance mitochondrial Ca2+ uptake and suppress cardiac arrhythmogenesis.
Sander P, Feng M, Schweitzer MK, Wilting F, Gutenthaler SM, Arduino DM, Fischbach S, Dreizehnter L, Moretti A, Gudermann T, Perocchi F, Schredelseker J.
Sander P, et al. Among authors: dreizehnter l.
Br J Pharmacol. 2021 Nov;178(22):4518-4532. doi: 10.1111/bph.15630. Epub 2021 Aug 18.
Br J Pharmacol. 2021.
PMID: 34287836
Free article.
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Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.
van den Boogaard M, Wong LY, Tessadori F, Bakker ML, Dreizehnter LK, Wakker V, Bezzina CR, 't Hoen PA, Bakkers J, Barnett P, Christoffels VM.
van den Boogaard M, et al. Among authors: dreizehnter lk.
J Clin Invest. 2012 Jul;122(7):2519-30. doi: 10.1172/JCI62613. Epub 2012 Jun 18.
J Clin Invest. 2012.
PMID: 22706305
Free PMC article.
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