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Small genomic insertions form enhancers that misregulate oncogenes.
Abraham BJ, Hnisz D, Weintraub AS, Kwiatkowski N, Li CH, Li Z, Weichert-Leahey N, Rahman S, Liu Y, Etchin J, Li B, Shen S, Lee TI, Zhang J, Look AT, Mansour MR, Young RA. Abraham BJ, et al. Among authors: rahman s. Nat Commun. 2017 Feb 9;8:14385. doi: 10.1038/ncomms14385. Nat Commun. 2017. PMID: 28181482 Free PMC article.
Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia.
Rahman S, Magnussen M, León TE, Farah N, Li Z, Abraham BJ, Alapi KZ, Mitchell RJ, Naughton T, Fielding AK, Pizzey A, Bustraan S, Allen C, Popa T, Pike-Overzet K, Garcia-Perez L, Gale RE, Linch DC, Staal FJT, Young RA, Look AT, Mansour MR. Rahman S, et al. Blood. 2017 Jun 15;129(24):3221-3226. doi: 10.1182/blood-2016-09-742148. Epub 2017 Mar 7. Blood. 2017. PMID: 28270453 Free PMC article.
Corrigendum: Small genomic insertions form enhancers that misregulate oncogenes.
Abraham BJ, Hnisz D, Weintraub AS, Kwiatkowski N, Li CH, Li Z, Weichert-Leahey N, Rahman S, Liu Y, Etchin J, Li B, Shen S, Lee TI, Zhang J, Look AT, Mansour MR, Young RA. Abraham BJ, et al. Among authors: rahman s. Nat Commun. 2017 Jun 1;8:15797. doi: 10.1038/ncomms15797. Nat Commun. 2017. PMID: 28569765 Free PMC article.
Prognostic impact of the absence of biallelic deletion at the TRG locus for pediatric patients with T-cell acute lymphoblastic leukemia treated on the Medical Research Council UK Acute Lymphoblastic Leukemia 2003 trial.
Farah N, Kirkwood AA, Rahman S, Leon T, Jenkinson S, Gale RE, Patrick K, Hancock J, Samarasinghe S, Linch DC, Moorman AV, Goulden N, Vora A, Mansour MR. Farah N, et al. Among authors: rahman s. Haematologica. 2018 Jul;103(7):e288-e292. doi: 10.3324/haematol.2017.185801. Epub 2018 Mar 8. Haematologica. 2018. PMID: 29519867 Free PMC article. No abstract available.
JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia.
Mansour MR, He S, Li Z, Lobbardi R, Abraham BJ, Hug C, Rahman S, Leon TE, Kuang YY, Zimmerman MW, Blonquist T, Gjini E, Gutierrez A, Tang Q, Garcia-Perez L, Pike-Overzet K, Anders L, Berezovskaya A, Zhou Y, Zon LI, Neuberg D, Fielding AK, Staal FJT, Langenau DM, Sanda T, Young RA, Look AT. Mansour MR, et al. Among authors: rahman s. J Exp Med. 2018 Jul 2;215(7):1929-1945. doi: 10.1084/jem.20170484. Epub 2018 Jun 25. J Exp Med. 2018. PMID: 29941549 Free PMC article.
The role of noncoding mutations in blood cancers.
Rahman S, Mansour MR. Rahman S, et al. Dis Model Mech. 2019 Nov 26;12(11):dmm041988. doi: 10.1242/dmm.041988. Dis Model Mech. 2019. PMID: 31771951 Free PMC article. Review.
EZH2-Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress.
León TE, Rapoz-D'Silva T, Bertoli C, Rahman S, Magnussen M, Philip B, Farah N, Richardson SE, Ahrabi S, Guerra-Assunção JA, Gupta R, Nacheva EP, Henderson S, Herrero J, Linch DC, de Bruin RAM, Mansour MR. León TE, et al. Among authors: rahman s. Cancer Discov. 2020 Jul;10(7):998-1017. doi: 10.1158/2159-8290.CD-19-0789. Epub 2020 Apr 29. Cancer Discov. 2020. PMID: 32349972 Free PMC article.
Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia.
Maciocia PM, Wawrzyniecka PA, Maciocia NC, Burley A, Karpanasamy T, Devereaux S, Hoekx M, O'Connor D, Leon T, Rapoz-D'Silva T, Pocock R, Rahman S, Gritti G, Yánez DC, Ross S, Crompton T, Williams O, Lee L, Pule MA, Mansour MR. Maciocia PM, et al. Among authors: rahman s. Blood. 2022 Jul 7;140(1):25-37. doi: 10.1182/blood.2021013648. Blood. 2022. PMID: 35507686 Free article.
The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia.
O'Connor D, Demeulemeester J, Conde L, Kirkwood A, Fung K, Papaleonidopoulou F, Bloye G, Farah N, Rahman S, Hancock J, Bateman C, Inglott S, Mee J, Herrero J, Van Loo P, Moorman AV, Vora A, Mansour MR. O'Connor D, et al. Among authors: rahman s. J Clin Oncol. 2023 Jul 1;41(19):3545-3556. doi: 10.1200/JCO.22.02734. Epub 2023 Apr 25. J Clin Oncol. 2023. PMID: 37098241 Free PMC article.
4,428 results