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Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries.
Imamura T, Fujita K, Tagawa K, Ikura T, Chen X, Homma H, Tamura T, Mao Y, Taniguchi JB, Motoki K, Nakabayashi M, Ito N, Yamada K, Tomii K, Okano H, Kaye J, Finkbeiner S, Okazawa H. Imamura T, et al. Among authors: finkbeiner s. Sci Rep. 2016 Sep 22;6:33861. doi: 10.1038/srep33861. Sci Rep. 2016. PMID: 27653664 Free PMC article.
Sequence-Level Analysis of the Major European Huntington Disease Haplotype.
Lee JM, Kim KH, Shin A, Chao MJ, Abu Elneel K, Gillis T, Mysore JS, Kaye JA, Zahed H, Kratter IH, Daub AC, Finkbeiner S, Li H, Roach JC, Goodman N, Hood L, Myers RH, MacDonald ME, Gusella JF. Lee JM, et al. Among authors: finkbeiner s. Am J Hum Genet. 2015 Sep 3;97(3):435-44. doi: 10.1016/j.ajhg.2015.07.017. Epub 2015 Aug 27. Am J Hum Genet. 2015. PMID: 26320893 Free PMC article.
High-throughput screening in primary neurons.
Sharma P, Ando DM, Daub A, Kaye JA, Finkbeiner S. Sharma P, et al. Among authors: finkbeiner s. Methods Enzymol. 2012;506:331-60. doi: 10.1016/B978-0-12-391856-7.00041-X. Methods Enzymol. 2012. PMID: 22341232 Free PMC article.
Huntington's Disease.
Finkbeiner S. Finkbeiner S. Cold Spring Harb Perspect Biol. 2011 Jun 1;3(6):a007476. doi: 10.1101/cshperspect.a007476. Cold Spring Harb Perspect Biol. 2011. PMID: 21441583 Free PMC article. Review.
231 results