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Liver-Kidney-on-Chip To Study Toxicity of Drug Metabolites.
Theobald J, Ghanem A, Wallisch P, Banaeiyan AA, Andrade-Navarro MA, Taškova K, Haltmeier M, Kurtz A, Becker H, Reuter S, Mrowka R, Cheng X, Wölfl S. Theobald J, et al. ACS Biomater Sci Eng. 2018 Jan 8;4(1):78-89. doi: 10.1021/acsbiomaterials.7b00417. Epub 2017 Dec 4. ACS Biomater Sci Eng. 2018. PMID: 33418680
Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs.
Cheng X, Kim JY, Ghafoory S, Duvaci T, Rafiee R, Theobald J, Alborzinia H, Holenya P, Fredebohm J, Merz KH, Mehrabi A, Hafezi M, Saffari A, Eisenbrand G, Hoheisel JD, Wölfl S. Cheng X, et al. Among authors: theobald j. Mol Oncol. 2016 Jun;10(6):806-24. doi: 10.1016/j.molonc.2016.01.008. Epub 2016 Feb 4. Mol Oncol. 2016. PMID: 26887594 Free PMC article.
Golgi stress mediates redox imbalance and ferroptosis in human cells.
Alborzinia H, Ignashkova TI, Dejure FR, Gendarme M, Theobald J, Wölfl S, Lindemann RK, Reiling JH. Alborzinia H, et al. Among authors: theobald j. Commun Biol. 2018 Nov 28;1:210. doi: 10.1038/s42003-018-0212-6. eCollection 2018. Commun Biol. 2018. PMID: 30511023 Free PMC article.
143 results