Molenaar P - Search Results

1

Ryanodine receptor modification and regulation by intracellular Ca²⁺ and Mg²⁺ in healthy and failing human hearts.

Walweel K, Molenaar P, Imtiaz MS, Denniss A, Dos Remedios C, van Helden DF, Dulhunty AF, Laver DR, Beard NA. Walweel K, et al. Among authors: molenaar p. J Mol Cell Cardiol. 2017 Mar;104:53-62. doi: 10.1016/j.yjmcc.2017.01.016. Epub 2017 Jan 26. J Mol Cell Cardiol. 2017. PMID: 28131631

2

Phenytoin Reduces Activity of Cardiac Ryanodine Receptor 2; A Potential Mechanism for Its Cardioprotective Action.

Ashna A, van Helden DF, Dos Remedios C, Molenaar P, Laver DR. Ashna A, et al. Among authors: molenaar p. Mol Pharmacol. 2020 Apr;97(4):250-258. doi: 10.1124/mol.119.117721. Epub 2020 Feb 3. Mol Pharmacol. 2020. PMID: 32015008

3

Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814.

Walweel K, Gomez-Hurtado N, Rebbeck RT, Oo YW, Beard NA, Molenaar P, Dos Remedios C, van Helden DF, Cornea RL, Knollmann BC, Laver DR. Walweel K, et al. Among authors: molenaar p. J Mol Cell Cardiol. 2019 May;130:96-106. doi: 10.1016/j.yjmcc.2019.03.018. Epub 2019 Mar 27. J Mol Cell Cardiol. 2019. PMID: 30928430 Free PMC article.

4

Differences in the regulation of RyR2 from human, sheep, and rat by Ca²⁺ and Mg²⁺ in the cytoplasm and in the lumen of the sarcoplasmic reticulum.

Walweel K, Li J, Molenaar P, Imtiaz MS, Quail A, dos Remedios CG, Beard NA, Dulhunty AF, van Helden DF, Laver DR. Walweel K, et al. Among authors: molenaar p. J Gen Physiol. 2014 Sep;144(3):263-71. doi: 10.1085/jgp.201311157. J Gen Physiol. 2014. PMID: 25156119 Free PMC article.

5

Sarcoplasmic reticulum calcium mishandling: central tenet in heart failure?

Denniss AL, Dashwood AM, Molenaar P, Beard NA. Denniss AL, et al. Among authors: molenaar p. Biophys Rev. 2020 Aug;12(4):865-878. doi: 10.1007/s12551-020-00736-y. Epub 2020 Jul 22. Biophys Rev. 2020. PMID: 32696300 Free PMC article. Review.

6

Understanding How Phosphorylation and Redox Modifications Regulate Cardiac Ryanodine Receptor Type 2 Activity to Produce an Arrhythmogenic Phenotype in Advanced Heart Failure.

Dashwood A, Cheesman E, Beard N, Haqqani H, Wong YW, Molenaar P. Dashwood A, et al. Among authors: molenaar p. ACS Pharmacol Transl Sci. 2020 Jun 1;3(4):563-582. doi: 10.1021/acsptsci.0c00003. eCollection 2020 Aug 14. ACS Pharmacol Transl Sci. 2020. PMID: 32832863 Free PMC article. Review.

7

Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation.

Foster SR, Porrello ER, Stefani M, Smith NJ, Molenaar P, dos Remedios CG, Thomas WG, Ramialison M. Foster SR, et al. Among authors: molenaar p. Naunyn Schmiedebergs Arch Pharmacol. 2015 Oct;388(10):1009-27. doi: 10.1007/s00210-015-1118-1. Epub 2015 May 20. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 25986534

8

Effects of omecamtiv mecarbil on failing human ventricular trabeculae and interaction with (-)-noradrenaline.

Dashwood A, Cheesman E, Wong YW, Haqqani H, Beard N, Hay K, Spratt M, Chan W, Molenaar P. Dashwood A, et al. Among authors: molenaar p. Pharmacol Res Perspect. 2021 May;9(3):e00760. doi: 10.1002/prp2.760. Pharmacol Res Perspect. 2021. PMID: 33929079 Free PMC article.

9

Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, K_Ca1.1, in Sinus Node Function and Arrhythmia Risk.

Pineda S, Nikolova-Krstevski V, Leimena C, Atkinson AJ, Altekoester AK, Cox CD, Jacoby A, Huttner IG, Ju YK, Soka M, Ohanian M, Trivedi G, Kalvakuri S, Birker K, Johnson R, Molenaar P, Kuchar D, Allen DG, van Helden DF, Harvey RP, Hill AP, Bodmer R, Vogler G, Dobrzynski H, Ocorr K, Fatkin D. Pineda S, et al. Among authors: molenaar p. Circ Genom Precis Med. 2021 Apr;14(2):e003144. doi: 10.1161/CIRCGEN.120.003144. Epub 2021 Feb 25. Circ Genom Precis Med. 2021. PMID: 33629867 Free PMC article.

10

(-)-Adrenaline elicits positive inotropic, lusitropic, and biochemical effects through beta2 -adrenoceptors in human atrial myocardium from nonfailing and failing hearts, consistent with Gs coupling but not with Gi coupling.

Molenaar P, Savarimuthu SM, Sarsero D, Chen L, Semmler AB, Carle A, Yang I, Bartel S, Vetter D, Beyerdörfer I, Krause EG, Kaumann AJ. Molenaar P, et al. Naunyn Schmiedebergs Arch Pharmacol. 2007 Mar;375(1):11-28. doi: 10.1007/s00210-007-0138-x. Epub 2007 Feb 13. Naunyn Schmiedebergs Arch Pharmacol. 2007. PMID: 17295024

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

392 results

Search Page