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Synthesis and preclinical evaluation of 2-(2-furanyl)-7-[2-[4-[4-(2-[11C]methoxyethoxy)phenyl]-1-piperazinyl]ethyl]7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine-5-amine ([11C]Preladenant) as a PET tracer for the imaging of cerebral adenosine A2A receptors.
Zhou X, Khanapur S, Huizing AP, Zijlma R, Schepers M, Dierckx RA, van Waarde A, de Vries EF, Elsinga PH. Zhou X, et al. J Med Chem. 2014 Nov 13;57(21):9204-10. doi: 10.1021/jm501065t. Epub 2014 Oct 15. J Med Chem. 2014. PMID: 25279444
Novel Approach to Repeated Arterial Blood Sampling in Small Animal PET: Application in a Test-Retest Study with the Adenosine A1 Receptor Ligand [(11)C]MPDX.
Sijbesma JW, Zhou X, Vállez García D, Houwertjes MC, Doorduin J, Kwizera C, Maas B, Meerlo P, Dierckx RA, Slart RH, Elsinga PH, van Waarde A. Sijbesma JW, et al. Among authors: zhou x. Mol Imaging Biol. 2016 Oct;18(5):715-23. doi: 10.1007/s11307-016-0954-9. Mol Imaging Biol. 2016. PMID: 27091332 Free PMC article.
Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models.
McMurray L, Macdonald JA, Ramakrishnan NK, Zhao Y, Williamson DW, Tietz O, Zhou X, Kealey S, Fagan SG, Smolek T, Cubinkova V, Žilka N, Spillantini MG, Tolkovsky AM, Goedert M, Aigbirhio FI. McMurray L, et al. Among authors: zhou x. ACS Chem Neurosci. 2021 Jun 2;12(11):1885-1893. doi: 10.1021/acschemneuro.0c00790. Epub 2021 Mar 10. ACS Chem Neurosci. 2021. PMID: 33689290 Free PMC article.
PET imaging of colony-stimulating factor 1 receptor: A head-to-head comparison of a novel radioligand, 11C-GW2580, and 11C-CPPC, in mouse models of acute and chronic neuroinflammation and a rhesus monkey.
Zhou X, Ji B, Seki C, Nagai Y, Minamimoto T, Fujinaga M, Zhang MR, Saito T, Saido TC, Suhara T, Kimura Y, Higuchi M. Zhou X, et al. J Cereb Blood Flow Metab. 2021 Sep;41(9):2410-2422. doi: 10.1177/0271678X211004146. Epub 2021 Mar 24. J Cereb Blood Flow Metab. 2021. PMID: 33757319 Free PMC article.
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