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Targeting the MAPK and PI3K pathways in combination with PD1 blockade in melanoma.
Deken MA, Gadiot J, Jordanova ES, Lacroix R, van Gool M, Kroon P, Pineda C, Geukes Foppen MH, Scolyer R, Song JY, Verbrugge I, Hoeller C, Dummer R, Haanen JB, Long GV, Blank CU. Deken MA, et al. Among authors: lacroix r. Oncoimmunology. 2016 Oct 14;5(12):e1238557. doi: 10.1080/2162402X.2016.1238557. eCollection 2016. Oncoimmunology. 2016. PMID: 28123875 Free PMC article.
Targeting tumor-associated acidity in cancer immunotherapy.
Lacroix R, Rozeman EA, Kreutz M, Renner K, Blank CU. Lacroix R, et al. Cancer Immunol Immunother. 2018 Sep;67(9):1331-1348. doi: 10.1007/s00262-018-2195-z. Epub 2018 Jul 5. Cancer Immunol Immunother. 2018. PMID: 29974196 Free PMC article. Review.
Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold.
Vredevoogd DW, Kuilman T, Ligtenberg MA, Boshuizen J, Stecker KE, de Bruijn B, Krijgsman O, Huang X, Kenski JCN, Lacroix R, Mezzadra R, Gomez-Eerland R, Yildiz M, Dagidir I, Apriamashvili G, Zandhuis N, van der Noort V, Visser NL, Blank CU, Altelaar M, Schumacher TN, Peeper DS. Vredevoogd DW, et al. Among authors: lacroix r. Cell. 2019 Jul 25;178(3):585-599.e15. doi: 10.1016/j.cell.2019.06.014. Epub 2019 Jul 11. Cell. 2019. PMID: 31303383 Free article.
Metabolic profiles of regulatory T cells in the tumour microenvironment.
Rao D, Verburg F, Renner K, Peeper DS, Lacroix R, Blank CU. Rao D, et al. Among authors: lacroix r. Cancer Immunol Immunother. 2021 Sep;70(9):2417-2427. doi: 10.1007/s00262-021-02881-z. Epub 2021 Feb 12. Cancer Immunol Immunother. 2021. PMID: 33576875 Free PMC article. Review.
Inhibitor of Apoptosis Proteins Antagonist Induces T-cell Proliferation after Cross-Presentation by Dendritic Cells.
Hoefsmit EP, van Royen PT, Rao D, Stunnenberg JA, Dimitriadis P, Lieftink C, Morris B, Rozeman EA, Reijers ILM, Lacroix R, Shehwana H, Ligtenberg MA, Beijersbergen RL, Peeper DS, Blank CU. Hoefsmit EP, et al. Among authors: lacroix r. Cancer Immunol Res. 2023 Apr 3;11(4):450-465. doi: 10.1158/2326-6066.CIR-22-0494. Cancer Immunol Res. 2023. PMID: 36753604
Acidity-mediated induction of FoxP3+ regulatory T cells.
Rao D, Stunnenberg JA, Lacroix R, Dimitriadis P, Kaplon J, Verburg F, van van Royen PT, Hoefsmit EP, Renner K, Blank CU, Peeper DS. Rao D, et al. Among authors: lacroix r. Eur J Immunol. 2023 Jun;53(6):e2250258. doi: 10.1002/eji.202250258. Epub 2023 Mar 19. Eur J Immunol. 2023. PMID: 36788428 Free article.
IMPemBra: a phase 2 study comparing pembrolizumab with intermittent/short-term dual MAPK pathway inhibition plus pembrolizumab in patients with melanoma harboring the BRAFV600 mutation.
Rozeman EA, Versluis JM, Sikorska K, Hoefsmit EP, Dimitriadis P, Rao D, Lacroix R, Grijpink-Ongering LG, Lopez-Yurda M, Heeres BC, van de Wiel BA, Flohil C, Sari A, Heijmink SWTPJ, van den Broek D, Broeks A, de Groot JWB, Vollebergh MA, Wilgenhof S, van Thienen JV, Haanen JBAG, Blank CU. Rozeman EA, et al. Among authors: lacroix r. J Immunother Cancer. 2023 Jul;11(7):e006821. doi: 10.1136/jitc-2023-006821. J Immunother Cancer. 2023. PMID: 37479483 Free PMC article. Clinical Trial.
Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold.
Vredevoogd DW, Kuilman T, Ligtenberg MA, Boshuizen J, Stecker KE, de Bruijn B, Krijgsman O, Huang X, Kenski JCN, Lacroix R, Mezzadra R, Gomez-Eerland R, Yildiz M, Dagidir I, Apriamashvili G, Zandhuis N, van der Noort V, Visser NL, Blank CU, Altelaar M, Schumacher TN, Peeper DS. Vredevoogd DW, et al. Among authors: lacroix r. Cell. 2020 Jan 23;180(2):404-405. doi: 10.1016/j.cell.2020.01.005. Cell. 2020. PMID: 31978349 Free article. No abstract available.
234 results