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Beta-agonist stimulation ameliorates the phenotype of spinal and bulbar muscular atrophy mice and patient-derived myotubes.
Milioto C, Malena A, Maino E, Polanco MJ, Marchioretti C, Borgia D, Pereira MG, Blaauw B, Lieberman AP, Venturini R, Plebani M, Sambataro F, Vergani L, Pegoraro E, Sorarù G, Pennuto M. Milioto C, et al. Among authors: lieberman ap. Sci Rep. 2017 Jan 24;7:41046. doi: 10.1038/srep41046. Sci Rep. 2017. PMID: 28117338 Free PMC article.
Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet.
Rocchi A, Milioto C, Parodi S, Armirotti A, Borgia D, Pellegrini M, Urciuolo A, Molon S, Morbidoni V, Marabita M, Romanello V, Gatto P, Blaauw B, Bonaldo P, Sambataro F, Robins DM, Lieberman AP, Sorarù G, Vergani L, Sandri M, Pennuto M. Rocchi A, et al. Among authors: lieberman ap. Acta Neuropathol. 2016 Jul;132(1):127-44. doi: 10.1007/s00401-016-1550-4. Epub 2016 Mar 12. Acta Neuropathol. 2016. PMID: 26971100 Free PMC article.
Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy.
Polanco MJ, Parodi S, Piol D, Stack C, Chivet M, Contestabile A, Miranda HC, Lievens PM, Espinoza S, Jochum T, Rocchi A, Grunseich C, Gainetdinov RR, Cato AC, Lieberman AP, La Spada AR, Sambataro F, Fischbeck KH, Gozes I, Pennuto M. Polanco MJ, et al. Among authors: lieberman ap. Sci Transl Med. 2016 Dec 21;8(370):370ra181. doi: 10.1126/scitranslmed.aaf9526. Sci Transl Med. 2016. PMID: 28003546
MEF2 impairment underlies skeletal muscle atrophy in polyglutamine disease.
Nath SR, Lieberman ML, Yu Z, Marchioretti C, Jones ST, Danby ECE, Van Pelt KM, Sorarù G, Robins DM, Bates GP, Pennuto M, Lieberman AP. Nath SR, et al. Among authors: lieberman ml, lieberman ap. Acta Neuropathol. 2020 Jul;140(1):63-80. doi: 10.1007/s00401-020-02156-4. Epub 2020 Apr 18. Acta Neuropathol. 2020. PMID: 32306066 Free PMC article.
Spinal and bulbar muscular atrophy.
Lieberman AP. Lieberman AP. Handb Clin Neurol. 2018;148:625-632. doi: 10.1016/B978-0-444-64076-5.00040-5. Handb Clin Neurol. 2018. PMID: 29478604 Review.
185 results