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Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management.
Bierzynska A, McCarthy HJ, Soderquest K, Sen ES, Colby E, Ding WY, Nabhan MM, Kerecuk L, Hegde S, Hughes D, Marks S, Feather S, Jones C, Webb NJ, Ognjanovic M, Christian M, Gilbert RD, Sinha MD, Lord GM, Simpson M, Koziell AB, Welsh GI, Saleem MA. Bierzynska A, et al. Among authors: koziell ab. Kidney Int. 2017 Apr;91(4):937-947. doi: 10.1016/j.kint.2016.10.013. Epub 2017 Jan 20. Kidney Int. 2017. PMID: 28117080 Free article.
Congenital nephrotic syndrome.
Koziell A, Iyer VK, Moghul NE, Ramani P, Taylor CM. Koziell A, et al. Pediatr Nephrol. 2001 Feb;16(2):185-9. doi: 10.1007/s004670000445. Pediatr Nephrol. 2001. PMID: 11261689
The human glomerular podocyte is a novel target for insulin action.
Coward RJ, Welsh GI, Yang J, Tasman C, Lennon R, Koziell A, Satchell S, Holman GD, Kerjaschki D, Tavaré JM, Mathieson PW, Saleem MA. Coward RJ, et al. Diabetes. 2005 Nov;54(11):3095-102. doi: 10.2337/diabetes.54.11.3095. Diabetes. 2005. PMID: 16249431
Nephrin deficiency activates NF-kappaB and promotes glomerular injury.
Hussain S, Romio L, Saleem M, Mathieson P, Serrano M, Moscat J, Diaz-Meco M, Scambler P, Koziell A. Hussain S, et al. J Am Soc Nephrol. 2009 Aug;20(8):1733-43. doi: 10.1681/ASN.2008111219. Epub 2009 Jun 4. J Am Soc Nephrol. 2009. PMID: 19497968 Free PMC article.
Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome.
McCarthy HJ, Bierzynska A, Wherlock M, Ognjanovic M, Kerecuk L, Hegde S, Feather S, Gilbert RD, Krischock L, Jones C, Sinha MD, Webb NJ, Christian M, Williams MM, Marks S, Koziell A, Welsh GI, Saleem MA; RADAR the UK SRNS Study Group. McCarthy HJ, et al. Clin J Am Soc Nephrol. 2013 Apr;8(4):637-48. doi: 10.2215/CJN.07200712. Epub 2013 Jan 24. Clin J Am Soc Nephrol. 2013. PMID: 23349334 Free PMC article.
Short course daily prednisolone therapy during an upper respiratory tract infection in children with relapsing steroid-sensitive nephrotic syndrome (PREDNOS 2): protocol for a randomised controlled trial.
Webb NJ, Frew E, Brettell EA, Milford DV, Bockenhauer D, Saleem MA, Christian M, Hall AS, Koziell A, Maxwell H, Hegde S, Finlay ER, Gilbert RD, Booth J, Jones C, McKeever K, Cook W, Ives NJ; PREDNOS 2 study group. Webb NJ, et al. Trials. 2014 Apr 27;15:147. doi: 10.1186/1745-6215-15-147. Trials. 2014. PMID: 24767719 Free PMC article. Clinical Trial.
Defects of CRB2 cause steroid-resistant nephrotic syndrome.
Ebarasi L, Ashraf S, Bierzynska A, Gee HY, McCarthy HJ, Lovric S, Sadowski CE, Pabst W, Vega-Warner V, Fang H, Koziell A, Simpson MA, Dursun I, Serdaroglu E, Levy S, Saleem MA, Hildebrandt F, Majumdar A. Ebarasi L, et al. Am J Hum Genet. 2015 Jan 8;96(1):153-61. doi: 10.1016/j.ajhg.2014.11.014. Epub 2014 Dec 31. Am J Hum Genet. 2015. PMID: 25557779 Free PMC article.
46 results