Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H(1)R.
Wittmann HJ, Seifert R, Strasser A.
Wittmann HJ, et al. Among authors: strasser a.
Biochem Pharmacol. 2011 Dec 15;82(12):1910-8. doi: 10.1016/j.bcp.2011.09.005. Epub 2011 Sep 16.
Biochem Pharmacol. 2011.
PMID: 21933664
Previous studies from our group revealed an influence of the exchange of N-terminus and E2-loop between hH(1)R and gpH(1)R onto affinity of phenoprodifen to H(1)R (Strasser A, Wittmann HJ, Seifert R, J Pharmacol Exp Ther 326:783-791, 2008). ...
Previous studies from our group revealed an influence of the exchange of N-terminus and E2-loop between hH(1)R and gpH(1)R onto affinity of …