Martinez RA - Search Results

1

A Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development.

Yao Z, Mich JK, Ku S, Menon V, Krostag AR, Martinez RA, Furchtgott L, Mulholland H, Bort S, Fuqua MA, Gregor BW, Hodge RD, Jayabalu A, May RC, Melton S, Nelson AM, Ngo NK, Shapovalova NV, Shehata SI, Smith MW, Tait LJ, Thompson CL, Thomsen ER, Ye C, Glass IA, Kaykas A, Yao S, Phillips JW, Grimley JS, Levi BP, Wang Y, Ramanathan S. Yao Z, et al. Among authors: martinez ra. Cell Stem Cell. 2017 Jan 5;20(1):120-134. doi: 10.1016/j.stem.2016.09.011. Epub 2016 Oct 27. Cell Stem Cell. 2017. PMID: 28094016 Free PMC article.

2

CORTECON: a temporal transcriptome analysis of in vitro human cerebral cortex development from human embryonic stem cells.

van de Leemput J, Boles NC, Kiehl TR, Corneo B, Lederman P, Menon V, Lee C, Martinez RA, Levi BP, Thompson CL, Yao S, Kaykas A, Temple S, Fasano CA. van de Leemput J, et al. Among authors: martinez ra. Neuron. 2014 Jul 2;83(1):51-68. doi: 10.1016/j.neuron.2014.05.013. Neuron. 2014. PMID: 24991954 Free article.

3

Genome engineering of isogenic human ES cells to model autism disorders.

Martinez RA, Stein JL, Krostag AR, Nelson AM, Marken JS, Menon V, May RC, Yao Z, Kaykas A, Geschwind DH, Grimley JS. Martinez RA, et al. Nucleic Acids Res. 2015 May 26;43(10):e65. doi: 10.1093/nar/gkv164. Epub 2015 Mar 11. Nucleic Acids Res. 2015. PMID: 25765640 Free PMC article.

4

Dynamics of embryonic stem cell differentiation inferred from single-cell transcriptomics show a series of transitions through discrete cell states.

Jang S, Choubey S, Furchtgott L, Zou LN, Doyle A, Menon V, Loew EB, Krostag AR, Martinez RA, Madisen L, Levi BP, Ramanathan S. Jang S, et al. Among authors: martinez ra. Elife. 2017 Mar 15;6:e20487. doi: 10.7554/eLife.20487. Elife. 2017. PMID: 28296635 Free PMC article.

5

A Rainbow Reporter Tracks Single Cells and Reveals Heterogeneous Cellular Dynamics among Pluripotent Stem Cells and Their Differentiated Derivatives.

El-Nachef D, Shi K, Beussman KM, Martinez R, Regier MC, Everett GW, Murry CE, Stevens KR, Young JE, Sniadecki NJ, Davis J. El-Nachef D, et al. Stem Cell Reports. 2020 Jul 14;15(1):226-241. doi: 10.1016/j.stemcr.2020.06.005. Epub 2020 Jul 2. Stem Cell Reports. 2020. PMID: 32619493 Free PMC article.

6

Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex.

Mich JK, Graybuck LT, Hess EE, Mahoney JT, Kojima Y, Ding Y, Somasundaram S, Miller JA, Kalmbach BE, Radaelli C, Gore BB, Weed N, Omstead V, Bishaw Y, Shapovalova NV, Martinez RA, Fong O, Yao S, Mortrud M, Chong P, Loftus L, Bertagnolli D, Goldy J, Casper T, Dee N, Opitz-Araya X, Cetin A, Smith KA, Gwinn RP, Cobbs C, Ko AL, Ojemann JG, Keene CD, Silbergeld DL, Sunkin SM, Gradinaru V, Horwitz GD, Zeng H, Tasic B, Lein ES, Ting JT, Levi BP. Mich JK, et al. Among authors: martinez ra. Cell Rep. 2021 Mar 30;34(13):108754. doi: 10.1016/j.celrep.2021.108754. Cell Rep. 2021. PMID: 33789096 Free PMC article.

7

Pharmacologic enhancement of retromer rescues endosomal pathology induced by defects in the Alzheimer's gene SORL1.

Mishra S, Knupp A, Kinoshita C, Williams CA, Rose SE, Martinez R, Theofilas P, Young JE. Mishra S, et al. Stem Cell Reports. 2023 Dec 12;18(12):2434-2450. doi: 10.1016/j.stemcr.2023.10.011. Epub 2023 Nov 9. Stem Cell Reports. 2023. PMID: 37949073 Free PMC article.

8

The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein.

Chakrabarti L, Neal JT, Miles M, Martinez RA, Smith AC, Sopher BL, La Spada AR. Chakrabarti L, et al. Among authors: martinez ra. Mamm Genome. 2006 Feb;17(2):103-10. doi: 10.1007/s00335-005-0096-x. Epub 2006 Feb 7. Mamm Genome. 2006. PMID: 16465590

9

Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing.

Knupp A, Mishra S, Martinez R, Braggin JE, Szabo M, Kinoshita C, Hailey DW, Small SA, Jayadev S, Young JE. Knupp A, et al. Cell Rep. 2020 Jun 2;31(9):107719. doi: 10.1016/j.celrep.2020.107719. Cell Rep. 2020. PMID: 32492427 Free PMC article.

10

Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk.

Young JE, Garden GA, Martinez RA, Tanaka F, Sandoval CM, Smith AC, Sopher BL, Lin A, Fischbeck KH, Ellerby LM, Morrison RS, Taylor JP, La Spada AR. Young JE, et al. Among authors: martinez ra. J Neurosci. 2009 Feb 18;29(7):1987-97. doi: 10.1523/JNEUROSCI.4072-08.2009. J Neurosci. 2009. PMID: 19228953 Free PMC article.

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