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Susceptibility to chronic social stress increases plaque progression, vulnerability and platelet activation.
Giannarelli C, Rodriguez DT, Zafar MU, Christoffel D, Vialou V, Peña C, Badimon A, Hodes GF, Mury P, Rabkin J, Alique M, Villa G, Argmann C, Nestler EJ, Russo SJ, Badimon JJ. Giannarelli C, et al. Among authors: rodriguez dt. Thromb Haemost. 2017 Apr 3;117(4):816-818. doi: 10.1160/TH16-10-0817. Epub 2017 Jan 12. Thromb Haemost. 2017. PMID: 28078352 Free PMC article. No abstract available.
Alternatively spliced tissue factor promotes plaque angiogenesis through the activation of hypoxia-inducible factor-1α and vascular endothelial growth factor signaling.
Giannarelli C, Alique M, Rodriguez DT, Yang DK, Jeong D, Calcagno C, Hutter R, Millon A, Kovacic JC, Weber T, Faries PL, Soff GA, Fayad ZA, Hajjar RJ, Fuster V, Badimon JJ. Giannarelli C, et al. Among authors: rodriguez dt. Circulation. 2014 Oct 7;130(15):1274-86. doi: 10.1161/CIRCULATIONAHA.114.006614. Epub 2014 Aug 12. Circulation. 2014. PMID: 25116956 Free PMC article.