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Discovery of 2-(((1r,4r)-4-(((4-Chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetate (Ralinepag): An Orally Active Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension.
Tran TA, Kramer B, Shin YJ, Vallar P, Boatman PD, Zou N, Sage CR, Gharbaoui T, Krishnan A, Pal B, Shakya SR, Garrido Montalban A, Adams JW, Ramirez J, Behan DP, Shifrina A, Blackburn A, Leakakos T, Shi Y, Morgan M, Sadeque A, Chen W, Unett DJ, Gaidarov I, Chen X, Chang S, Shu HH, Tung SF, Semple G. Tran TA, et al. Among authors: krishnan a. J Med Chem. 2017 Feb 9;60(3):913-927. doi: 10.1021/acs.jmedchem.6b00871. Epub 2017 Jan 19. J Med Chem. 2017. PMID: 28072531
Fused tricyclic indoles as S1P₁ agonists with robust efficacy in animal models of autoimmune disease.
Buzard DJ, Han S, Lopez L, Kawasaki A, Moody J, Thoresen L, Ullman B, Lehmann J, Calderon I, Zhu X, Gharbaoui T, Sengupta D, Krishnan A, Gao Y, Edwards J, Barden J, Morgan M, Usmani K, Chen C, Sadeque A, Thatte J, Solomon M, Fu L, Whelan K, Liu L, Al-Shamma H, Gatlin J, Le M, Xing C, Espinola S, Jones RM. Buzard DJ, et al. Among authors: krishnan a. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4404-9. doi: 10.1016/j.bmcl.2012.04.129. Epub 2012 May 7. Bioorg Med Chem Lett. 2012. PMID: 22633692
(7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P1 Functional Antagonists.
Buzard DJ, Lopez L, Moody J, Kawasaki A, Schrader TO, Kasem M, Johnson B, Zhu X, Thoresen L, Kim SH, Gharbaoui T, Sengupta D, Calvano L, Krishnan A, Gao Y, Semple G, Edwards J, Barden J, Morgan M, Usmani K, Chen C, Sadeque A, Chen W, Christopher RJ, Thatte J, Fu L, Solomon M, Whelan K, Al-Shamma H, Gatlin J, Gaidarov I, Anthony T, Le M, Unett DJ, Stirn S, Blackburn A, Behan DP, Jones RM. Buzard DJ, et al. Among authors: krishnan a. ACS Med Chem Lett. 2014 Nov 25;5(12):1334-9. doi: 10.1021/ml500422m. eCollection 2014 Dec 11. ACS Med Chem Lett. 2014. PMID: 25516794 Free PMC article.
Longitudinal Multimodal Transformer Integrating Imaging and Latent Clinical Signatures From Routine EHRs for Pulmonary Nodule Classification.
Li TZ, Still JM, Xu K, Lee HH, Cai LY, Krishnan AR, Gao R, Khan MS, Antic S, Kammer M, Sandler KL, Maldonado F, Landman BA, Lasko TA. Li TZ, et al. Among authors: krishnan ar. Med Image Comput Comput Assist Interv. 2023 Oct;14221:649-659. doi: 10.1007/978-3-031-43895-0_61. Epub 2023 Oct 1. Med Image Comput Comput Assist Interv. 2023. PMID: 38779102 Free PMC article.
Common mental disorders among adolescents in an urban area of Delhi.
Ahmad A, Salve HR, Nongkynrih B, Sagar R, Krishnan A. Ahmad A, et al. Among authors: krishnan a. Indian J Psychiatry. 2024 Apr;66(4):347-351. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_728_22. Epub 2024 Apr 22. Indian J Psychiatry. 2024. PMID: 38778841 Free PMC article.
A deep learning framework for noninvasive fetal ECG signal extraction.
Wahbah M, Zitouni MS, Al Sakaji R, Funamoto K, Widatalla N, Krishnan A, Kimura Y, Khandoker AH. Wahbah M, et al. Among authors: krishnan a. Front Physiol. 2024 Apr 22;15:1329313. doi: 10.3389/fphys.2024.1329313. eCollection 2024. Front Physiol. 2024. PMID: 38711954 Free PMC article.
Awareness, attitudes, and practices regarding meningococcal serogroup B vaccination in the United States among parents of older adolescents and among young adults: a plain language summary.
Herrera-Restrepo O, Zhou Z, Krishnan A, Conley WJ, Oladele E, Multani JK, Tuly R, Shi L, Chen CC, Preiss S, Clements DE. Herrera-Restrepo O, et al. Among authors: krishnan a. Curr Med Res Opin. 2024 May 6:1-4. doi: 10.1080/03007995.2024.2307342. Online ahead of print. Curr Med Res Opin. 2024. PMID: 38709213 No abstract available.
Minimal Residual Disease Status in Multiple Myeloma 1 Year After Autologous Hematopoietic Cell Transplantation and Lenalidomide Maintenance Are Associated With Long-Term Overall Survival.
Pasquini MC, Wallace PK, Logan B, Kaur M, Tario JD, Howard A, Zhang Y, Brunstein C, Efebera Y, Geller N, Giralt S, Hari P, Horowitz MM, Koreth J, Krishnan A, Landau H, Somlo G, Shah N, Stadtmauer E, Vogl DT, Vesole DH, McCarthy PL, Hahn T. Pasquini MC, et al. Among authors: krishnan a. J Clin Oncol. 2024 May 3:JCO2300934. doi: 10.1200/JCO.23.00934. Online ahead of print. J Clin Oncol. 2024. PMID: 38701390
Designing combination therapies for cancer treatment: application of a mathematical framework combining CAR T-cell immunotherapy and targeted radionuclide therapy.
Adhikarla V, Awuah D, Caserta E, Minnix M, Kuznetsov M, Krishnan A, Wong JYC, Shively JE, Wang X, Pichiorri F, Rockne RC. Adhikarla V, et al. Among authors: krishnan a. Front Immunol. 2024 Apr 18;15:1358478. doi: 10.3389/fimmu.2024.1358478. eCollection 2024. Front Immunol. 2024. PMID: 38698840 Free PMC article.
1,912 results