Turkenburg JP - Search Results

1

Structural and functional insights into asymmetric enzymatic dehydration of alkenols.

Nestl BM, Geinitz C, Popa S, Rizek S, Haselbeck RJ, Stephen R, Noble MA, Fischer MP, Ralph EC, Hau HT, Man H, Omar M, Turkenburg JP, van Dien S, Culler SJ, Grogan G, Hauer B. Nestl BM, et al. Among authors: turkenburg jp. Nat Chem Biol. 2017 Mar;13(3):275-281. doi: 10.1038/nchembio.2271. Epub 2017 Jan 9. Nat Chem Biol. 2017. PMID: 28068311 Free article.

2

The 2-A crystal structure of 6-oxo camphor hydrolase. New structural diversity in the crotonase superfamily.

Whittingham JL, Turkenburg JP, Verma CS, Walsh MA, Grogan G. Whittingham JL, et al. Among authors: turkenburg jp. J Biol Chem. 2003 Jan 17;278(3):1744-50. doi: 10.1074/jbc.M211188200. Epub 2002 Nov 5. J Biol Chem. 2003. PMID: 12421807 Free article.

3

The structure of monoamine oxidase from Aspergillus niger provides a molecular context for improvements in activity obtained by directed evolution.

Atkin KE, Reiss R, Koehler V, Bailey KR, Hart S, Turkenburg JP, Turner NJ, Brzozowski AM, Grogan G. Atkin KE, et al. Among authors: turkenburg jp. J Mol Biol. 2008 Dec 31;384(5):1218-31. doi: 10.1016/j.jmb.2008.09.090. Epub 2008 Oct 14. J Mol Biol. 2008. PMID: 18951902

4

The 1.5-A structure of XplA-heme, an unusual cytochrome P450 heme domain that catalyzes reductive biotransformation of royal demolition explosive.

Sabbadin F, Jackson R, Haider K, Tampi G, Turkenburg JP, Hart S, Bruce NC, Grogan G. Sabbadin F, et al. Among authors: turkenburg jp. J Biol Chem. 2009 Oct 9;284(41):28467-28475. doi: 10.1074/jbc.M109.031559. Epub 2009 Aug 19. J Biol Chem. 2009. PMID: 19692330 Free PMC article.

5

A covalent succinylcysteine-like intermediate in the enzyme-catalyzed transformation of maleate to fumarate by maleate isomerase.

Fisch F, Fleites CM, Delenne M, Baudendistel N, Hauer B, Turkenburg JP, Hart S, Bruce NC, Grogan G. Fisch F, et al. Among authors: turkenburg jp. J Am Chem Soc. 2010 Aug 25;132(33):11455-7. doi: 10.1021/ja1053576. J Am Chem Soc. 2010. PMID: 20677745

6

A flavoprotein monooxygenase that catalyses a Baeyer-Villiger reaction and thioether oxidation using NADH as the nicotinamide cofactor.

Jensen CN, Cartwright J, Ward J, Hart S, Turkenburg JP, Ali ST, Allen MJ, Grogan G. Jensen CN, et al. Among authors: turkenburg jp. Chembiochem. 2012 Apr 16;13(6):872-8. doi: 10.1002/cbic.201200006. Epub 2012 Mar 13. Chembiochem. 2012. PMID: 22416037

7

Structures of a γ-aminobutyrate (GABA) transaminase from the s-triazine-degrading organism Arthrobacter aurescens TC1 in complex with PLP and with its external aldimine PLP-GABA adduct.

Bruce H, Nguyen Tuan A, Mangas Sánchez J, Leese C, Hopwood J, Hyde R, Hart S, Turkenburg JP, Grogan G. Bruce H, et al. Among authors: turkenburg jp. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1175-80. doi: 10.1107/S1744309112030023. Epub 2012 Sep 29. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 23027742 Free PMC article.

8

Structure and activity of NADPH-dependent reductase Q1EQE0 from Streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate.

Rodríguez-Mata M, Frank A, Wells E, Leipold F, Turner NJ, Hart S, Turkenburg JP, Grogan G. Rodríguez-Mata M, et al. Among authors: turkenburg jp. Chembiochem. 2013 Jul 22;14(11):1372-9. doi: 10.1002/cbic.201300321. Epub 2013 Jun 28. Chembiochem. 2013. PMID: 23813853

9

Structures of the Apo and FAD-bound forms of 2-hydroxybiphenyl 3-monooxygenase (HbpA) locate activity hotspots identified by using directed evolution.

Jensen CN, Mielke T, Farrugia JE, Frank A, Man H, Hart S, Turkenburg JP, Grogan G. Jensen CN, et al. Among authors: turkenburg jp. Chembiochem. 2015 Apr 13;16(6):968-76. doi: 10.1002/cbic.201402701. Epub 2015 Mar 3. Chembiochem. 2015. PMID: 25737306 Free PMC article.

10

Structure, Activity and Stereoselectivity of NADPH-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline.

Man H, Wells E, Hussain S, Leipold F, Hart S, Turkenburg JP, Turner NJ, Grogan G. Man H, et al. Among authors: turkenburg jp. Chembiochem. 2015 May 4;16(7):1052-9. doi: 10.1002/cbic.201402625. Epub 2015 Mar 24. Chembiochem. 2015. PMID: 25809902

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