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The random co-polymer glatiramer acetate rapidly kills primary human leukocytes through sialic-acid-dependent cell membrane damage.
Christiansen SH, Zhang X, Juul-Madsen K, Hvam ML, Vad BS, Behrens MA, Thygesen IL, Jalilian B, Pedersen JS, Howard KA, Otzen DE, Vorup-Jensen T. Christiansen SH, et al. Among authors: howard ka. Biochim Biophys Acta Biomembr. 2017 Mar;1859(3):425-437. doi: 10.1016/j.bbamem.2017.01.001. Epub 2017 Jan 5. Biochim Biophys Acta Biomembr. 2017. PMID: 28064019 Free article.
Albumin-based drug delivery: harnessing nature to cure disease.
Larsen MT, Kuhlmann M, Hvam ML, Howard KA. Larsen MT, et al. Among authors: howard ka. Mol Cell Ther. 2016 Feb 27;4:3. doi: 10.1186/s40591-016-0048-8. eCollection 2016. Mol Cell Ther. 2016. PMID: 26925240 Free PMC article. Review.
The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria.
Christiansen SH, Murphy RA, Juul-Madsen K, Fredborg M, Hvam ML, Axelgaard E, Skovdal SM, Meyer RL, Sørensen UBS, Möller A, Nyengaard JR, Nørskov-Lauritsen N, Wang M, Gadjeva M, Howard KA, Davies JC, Petersen E, Vorup-Jensen T. Christiansen SH, et al. Among authors: howard ka. Sci Rep. 2017 Nov 15;7(1):15653. doi: 10.1038/s41598-017-15969-3. Sci Rep. 2017. PMID: 29142299 Free PMC article.
162 results